ADALIMUMAB

COMMON BRAND NAME(S): Humira

GENERIC NAME(S): ADALIMUMAB

 

Description: Adalimumab is interferes with the inflammatory processes. It is used for the management of rheumatoid arthritis.

Adalimumab is an anti-inflammatory drug used in certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, ankylosing spondylitis); also in psoriasis (plaque-type), certain bowel conditions (Crohn’s disease, ulcerative colitis).

How to use adalimumab subcutaneous

  • Do not shake or warm this medication.
  • Follow the instructions and prescription of the doctor for the specific purposes of the drug.
  • When injecting each dose, make sure to clean the skin area and do not inject into any areas of the skin that are sore, bruised, red, or hard.

Adalimumab can decrease your body’s ability to fight an infection leading to fungal and bacterial infections (such as Tuberculosis).

Developing lymphoma is unlikely but there is a risk.

The side effects of adalimumab include: Redness, itching, pain, or swelling at the injection site may occur.

Signs of infection while using this drug, are: sore throat that doesn’t go away, cough that doesn’t go away, fever, chills, night sweats, trouble breathing, painful or frequent urination, unusual vaginal discharge, white patches in the mouth (oral thrush).

Serious side effects, include: swelling ankles/feet, unusual tiredness, fast/irregular/pounding heartbeat, blood in the stools, mental/mood changes, severe headache, easy bruising or bleeding, leg pain or swelling, numbness or tingling of the arms/hands/legs/feet, unsteadiness, unexplained muscle weakness, difficulty with speaking/chewing/swallowing/facial movements, vision changes, joint pain, butterfly-shaped rash on the nose and cheeks.

In people exposed to hepatitis B virus, Adalimumab may rarely cause fatal liver disease. Symptoms of liver damage, include: nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.

Seizures and chest pain are other side effects.

If you experience these symptoms and In case of allergic reactions, consult your doctor immediately.

Precautions

Inform your doctor or pharmacist your allergies, medical history, especially especially of: current/recent/repeated infections (such as hepatitis B, TB infection, histoplasmosis), blood/bone marrow problems (such as low red/white blood cells and platelets), seizures, certain brain/nerve disorders (such as multiple sclerosis, Guillain-Barre syndrome), cancer, heart disease (especially heart failure), lupus.

Because it depresses the immune system, do not have immunizations/vaccinations and avoid contact with people who recently received live vaccine.

For pregnant and breastfeeding mothers, consult your doctor before use.

 

Interactions

Products that may interact with this drug include: other TNF blockers (such as etanercept, infliximab), other drugs that weaken the immune system (such as abatacept, anakinra, tofacitinib).

Overdose

Get emergency medical help when overdose is suspected.

Missed Dose: As soon as you remember, take a regular dose or if the time of the next dose is near, wait for it before taking another dose and resume your usual schedule. Do not increase the dose to compensate for the missed dose.

Storage: Store medications in Room temperature Do not expose to light and moisture Do not store in the bathroom Keep all medications away from pets and children Do not flush medications down the toilet or pour into a drain.

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