Alogliptin + Metformin is a combination drug that is made up of Alogliptin and Metformin, two medicines for diabetes. Alogliptin inhibits the enzyme dipeptidylpeptidase-4 (DPP-4), further increasing incretin hormone levels that leads to decreased glucose production in the liver. Metformin is a biguanide medicine that reduces the production of glucose in the liver and makes the body tissues sensitive to insulin.