VIGABATRIN

Vigabatrin is an anticonvulsant that works by stopping the breakdown of a natural calming substance (GABA) in the brain.

This medication is used in combination with other medications to control certain types of seizures in adults and children 10 years of age or older whose seizures were not controlled by several other medications. Vigabatrin powder is used to control infantile spasms (a type of seizure that babies and children can have) in babies 1 month to 2 years of age.

Vigabatrin may cause permanent vision loss in a high percentage of patients. This effect may occur within weeks or sooner after starting treatment. It may also occur after months or years. The risk may increase with higher doses and prolonged use, but it may occur with any dose or length of use. Vision loss may continue to worsen after stopping vigabatrin.

Common side effects may include:

  • Sleepiness
  • Dizziness
  • Uncontrollable Shaking of a Part of the Body
  • Weakness
  • Joint or Muscle Pain
  • Problems Walking or Feeling Uncoordinated
  • Memory Problems and not Thinking Clearly
  • Weight Gain
  • Swelling of The Hands, Feet, Ankles, or Lower Legs
  • Pain, Burning, or Tingling in the Hands or Feet
  • Fever
  • Irritability
  • Diarrhea
  • Nausea
  • Vomiting
  • Constipation
  • Stomach Pain
  • Heartburn
  • Severely Painful Cramps During Menstrual Period

Notify your doctor if any of these symptoms persist or worsen.

Serious side effects may include:

  • Confusion
  • Tiredness
  • Pale Skin
  • Fast Heartbeat
  • Difficulty Breathing
  • Hives
  • Itching

Precautions

Before using Vigabatrin tell your doctor or pharmacist if you have any medical conditions, especially if any of the following:

  • If you are pregnant, planning to become pregnant, or are breast-feeding
  • If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • If you have allergies to medicines, foods, or other substances
  • If you have vision problems, kidney problems, or certain blood problems (eg, anemia, porphyria)
  • If you have a history of depression, other mental or mood problems, or suicidal thoughts or actions

 

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. Tell your doctor all the products you use including prescription/nonprescription drugs and herbal products.

Some products may interact with this drug including:

  • Drugs that can Harm the Eye (retinotoxic drugs such as Chloroquine, Hydroxychloroquine, Phenothiazines including thioridazine)
  • Orlistat

 

 

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

  • Drowsiness
  • Loss of Consciousness

 

Available brand/s:

  • Vigabatrin

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