COMMON BRAND NAME(S): Chantix
GENERIC NAME(S): VARENICLINE TARTRATE
Description: Varenicline is a smoking cessation agent that blocks the pleasurable effects of smoking in the brain and helps to decrease the desire to smoke.
Absorption: Well absorbed from the GI tract. Bioavailability: Approx 90%. Highest concentration in the blood 3 to 4 hours after taking the drug.
Distribution: Plasma protein binding: <20%.
Metabolism: Minimal metabolism.
Excretion: Via urine (approx 92% as unchanged drug, <10% as metabolites). Elimination half-life: Approx 24 hr.