VACCINE, BCG

BCG vaccine is a live strain of bacillus Calmette-Guérin and is used for the active immunization against tuberculosis. It is also used as an active immunotherapy for bladder cancer.

BCG vaccine is used in the following:

  • Active immunisation against tuberculosis
  • Immunotherapy of bladder cancer

BCG vaccine should not be used in people with the following conditions:

  • Hypersensitivity
  • Patients who are immunocompromised
  • HIV-infected
  • Have fever
  • Burn patients
  • Active tuberculosis
  • Urinary tract infection
  • Gross haematuria
  • Recent (<7-14 days) biopsy
  • Transurethral resection (TUR)
  • Traumatic catheterisation

BCG vaccine may give rise to the following side effects:

  • Malaise
  • Fever
  • Chills
  • Nausea
  • Vomiting
  • Weight loss
  • Anorexia
  • Bladder irritation
  • Dysuria
  • Polyuria
  • Haematuria
  • Cystitis
  • Urinary urgency
  • Urinary tract infections
  • Anaemia
  • Flu-like syndrome

Precautions

Extra caution should be observed on people with the following conditions:

  • Persons at high risk for HIV
  • Severely immunocompromised patients
  • Persons with a positive PPD reaction
  • People on antimicrobial treatment (bladder administration)
  • Patients with small bladder capacity due to increased risk of local reactions
  • Persistent fever
  • Fever due to BCG infection
  • Pregnancy and lactation

 

Interactions

BCG vaccine may interact with the following medicines:

  • Antimicrobials
  • Immune globulins
  • Immunosuppressants
  • Live vaccines

If you have used BCG vaccine more than its recommended dose, seek medical help immediately.

 

Available Brands:

  • Euro BCG
  • Euro Pharma BCG Vaccine
  • Japan BCG
  • Onco-BCG

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