SODIUM PHOSPHATE

Management of hypophosphataemia. Also used as a mild laxative

 

DOSAGE

  • Adult : By mouth
    • Hypophosphataemia ≤100 mmol of phosphate/day. IV Severe hypophosphataemia As monobasic potassium phosphate: ≤9 mmol of phosphate, repeat 12 hrly if needed.
  • Rectal
    • Mild osmotic laxative for bowel evacuation and cleansing Solution containing monobasic and dibasic sodium phosphates in various compositions. Use as directed.
  • Should not be used in patients with the following conditions:
    • Severe renal function, congestive heart failure, ascites, unstable angina pectoris, gastric retention, ileus or acute obstruction or pseudo-obstruction, severe chronic constipation, bowel perforation, acute colitis, toxic megacolon or hypomotility syndrome, hypertension, hyperkalaemia, oedema, low serum-calcium concentrations, infected phosphate renal calculi.
  • Caution for use in patients with Chronic renal disease, pre-existing electrolyte disturbances. Concurrent admin with drugs that may affect electrolyte levels, elderly or debilitated patients.
  • If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.

Abdominal discomfort or pain, diarrhoea, nausea, vomiting, hypernatraemia, dehydration (with high doses). Convulsions, drowsiness, mood change, trembling, malaise, loss of appetite, muscle spasm (with long-term use). Less frequently, headaches, dizziness, mental confusion, seizures, weakness or heaviness of legs, muscle cramps, numbness, tingling, pain, arrhythmia; shortness of breath or troubled breathing; swelling of lower legs or feet; unusual weight gain, low urine output; unusual thirst; bone and joint pain.

If overdose is suspected, contact a poison control center or emergency room immediately.

  • May lead to severe electrolyte disturbances, including hyperphosphataemia, hypocalcaemia, hypernatraemia, or hypokalaemia, as well as dehydration and hypovolaemia, cardiac arrhythmias, seizure, renal failure and death.

 

DRUG INTERACTIONS

Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

Products that may interact with this medication include:

  • aluminium, calcium, or magnesium salts, Vitamin D, diuretics or drugs that may affect serum electrolytes, calcium supplements or calcium-containing antacids such as milk or dairy products

 

STORAGE

Oral:

Store at 15-30°C.

Rectal:

Store at 15-30°C.

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