RETIGABINE

Retigabine is a drug that is used to treat seizures. This medicine leads to the activation of specific potassium channels in the brain that are known as KCNQ (Kv7.2-7.5) ion channels. This leads to stable potassium channel open formation, further enhancing the M-type current and applying a hyperpolarising impact on nerve cells. This further leads to the stabilization of the resting membrane potential and prevention of seizures.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Retigabine is used in the following conditions:

Adjunct in partial seizures.

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Retigabine in people with the following conditions:

Hypersensitivity reactions

Side Effects

Retigabine may have the following side effects:

Dizziness
Somnolence
Fatigue
Confusional state
Aphasia
Abnormal coordination
Tremor
Balance disorder
Memory impairment
Gait disturbance
Blurred vision
Constipation
Anxiety
Psychotic disorders
Paraesthesia
Weight gain
Nausea
Dyspepsia
Urinary retention and hesitation
Dysuria
Discolouration of ocular tissues (including the retina) skin, lips, and nails
Prolongation of QT interval

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist

Precautions

Take extra caution in patients with the following medical conditions:

Patient withknown QT interval prolongation
Ventricular hypertrophy
Hypokalemia
Hypomagnesemia
Those at risk of urinary retention
Avoid abrupt withdrawal
Moderate to severe hepatic or renal impairment (CrCl <50 mL/min)
Elderly
Pregnancy
Lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Retigabine may interact with the following medicines:

Thiopental sodium
Quinidine
Amiodarone
Chlorpromazine
Clarithromycin
Phenytoin
Carbamazepine

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

Symptoms of overdose may include the following:

Agitation
aggressive behaviour
Irritability
cardiac arrhythmia

Seek medical help immediately.

Available Brands:

Trobalt
Potiga