REBOXETINE

Reboxetine should be used with caution in:

• Those under 18 years of age
• The elderly
• Patients with heart disease or epilepsy
• Those with poor liver or kidney function
• Previous or current mental diseases such as mania or psychose
• Increased pressure in the eye (known as narrow-angle glaucoma)
• Those who have problems urinating or with an enlarged prostate

Side effects of this drug include:

• Nausea (feeling sick)
• Dryness of the mouth
• Insomnia (unable to sleep)
• Headache
• Constipation
• Dizziness
• Excessive sweating
• Rapid heart beat (tachycardia)
• Flushing
• Feeling faint on standing
• Chills
• Impaired sight (difficulty focusing)
• Decreased appetite
• Difficulty urinating, or sense of incomplete emptying of the bladder
• Sexual problems (e.g. problems with erection or delayed ejaculation in men)

Tell your doctor promptly if any of these effects persist or worsen.

Precautions

Before taking Reboxetine, tell your doctor or pharmacist if you are allergic to it; or to other antidepressants; or if you have any other allergies.

Before using this medicine, consult your doctor or pharmacist if you have:

• Mental disorders (particularly schizophrenia or bipolar disorder)
• Epilepsy
• Liver or kidney disease or any sort of heart or blood disorder
• Increased pressure in the eye (glaucoma)
• Prostate problems or problems with urinating
• Or if you are pregnant or likely to become pregnant or are breastfeeding.

Before using this medication, tell your doctor or pharmacist your medical history, especially any episodes of mania (overactive behaviour or thoughts)

Interactions

Drug interactions may interfere with how your medication works. Notify your doctor and pharmacist about all of your medications and health problems so they can check for any interactions with this medication.

The following medicines may interact with Reboxetine:

• Other antidepressants, such as monoamine oxidase inhibitors (MAOIs), including the reversible MAOI moclobemibe; and the selective serotonin reuptake inhibitor (SSRI) fluvoxamine)
• Antibiotics (macrolides such as erythromycin, azithromycin and clarithromycin)
• Antifungal agents e.g. ketoconazole, fluconazole and itraconazole
• Diuretics, such as bendroflumethiazide, indapamide or furosemide
• Atomoxetine, used to treat attention deficit hyperactivity disorder (ADHD)
• Ergot derivatives, used to treat migraine or Parkinson’s disease (e.g. ergotamine and methysergide)
• Medicines used to treat epilepsy, such as phenytoin, carbamazepine or phenobarbital

For more details, talk to your doctor or pharmacist.

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing. Symptoms of an overdose include:

• Feeling Faint On Standing
• Anxiety
• High Blood Pressure (Hypertension)

Available brands:

• Reboxetine