RALTEGRAVIR

Raltegravir is a drug that belongs to a class of medicines known as HIV integrase inhibitors. HIV integrase is an enzyme necessary for insertion of viral DNA into the host cell genome. This further inhibits viral gene expression and replication.

It is active against HIV-1 and HIV-2.

Uses

Raltegravir is used to treat HIV-1 infection.

Warnings

Raltegravir should not be used by people who are allergic to it. Do not give in lactating women.

Side Effects

Raltegravir may have the following side effects such as:

Rash
Myopathy
Rhabdomyolysis
Osteonecrosis
Increased creatine phosphokinase
Immune reconstitution syndrome
Depression
Suicidal ideation
Paranoia
Anxiety
Insomnia
Abnormal dreams
Headache
Dizziness
Asthenia
Fatigue
Vertigo
Hyperactivity
Abdominal pain
Diarrhoea
Nausea
Vomiting
Gastritis
Flatulence
Increased transaminases and bilirubin
Hepatitis
Renal failure
Increased triglycerides and cholesterol
Hyperglycaemia
Neutropenia
Thrombocytopenia
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Organ dysfunction (e.g. hepatic failure)

Precautions

Precautions

Precautions should be observed in the following cases:

History of myopathy
Rhabdomyolysis
Depression
Psychiatric illness
Concomitant rifampicin treatment
Severe hepatic impairment (e.g. chronic hepatitis B or C)
Children
Pregnancy

Interactions

Raltegravir may interact with rifampicin and Al- and Mg-containing antacids.

Overdose & Brands

If you think you have overdosed, seek medical help immediately.

Available Brand:

Isentress