HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

QUINAPRIL + HYDROCHLOROTHIAZIDE

Quinapril + Hydrochlorothiazide is a combination of ACE inhibitor and thiazide diuretic, respectively. They both reduce blood pressure through different but synergistic activities. Hydrochlorothiazide decreases blood pressure and volume and at the same time it increases the levels of angiotensin II which will be blocked by quinapril, resulting in an additive antihypertensive effect.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully. 

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages. 

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day. 

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions. 

If you have any inquiries with regards to information, ask your physician or pharmacist.

Quinapril + Hydrochlorothiazideis used in the following conditions:

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.  

Do not use Quinapril + Hydrochlorothiazide in people with the following conditions:

  • Hypertensive
  • History of angioedema to previous ACE inhibitor treatment
  • Hereditary or idiopathic angioneurotic edema
  • Dynamic left ventricular outflow obstruction
  • Anuria
  • Severe renal impairment
  • Pregnancy

Quinapril + Hydrochlorothiazide may have the following side effects:

  • Symptomatic hypotension with or without syncope
  • Intestinal angioedema
  • Electrolyte disturbances
  • Cough
  • Gout
  • Hematologic effects
  • Ocular effects
  • Sensitivity reactions
  • Non-melanoma skin cancer
  • Stevens-Johnson syndrome
  • SLE exacerbation or activation
  • Elevated BUN 
  • Increased serum creatinine
  • Oliguria
  • Progressive azotaemia
  • Angina pectoris
  • Tachycardia
  • Palpitation
  • Tinnitus
  • Amblyopia
  • Blurred vision
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Dry mouth
  • Fatigue
  • Asthenia
  • Pyrexia
  • Edema
  • Hepatitis
  • Urticaria
  • Elevated hepatic enzymes
  • Hyperuricemia
  • Impaires glucose tolerance
  • Back pain
  • Myalgia
  • Headache
  • Dizziness
  • Somnolence
  • Vertigo
  • Insomnia
  • Confusion
  • Depression
  • Dyspnea
  • Bronchitis
  • Sinusitis
  • Rash
  • Pruritus
  • Alopecia
  • Hyperhidrosis
  • Vasodilation
  • Orthostatic hypotension
  • Potentially fatal: Laryngeal angioedema, arrhythmia. Rarely, cholestatic jaundice progressing to fulminant hepatic necrosis, acute renal failure, anaphylactoid reactions.

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.  

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing. 

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Patient with adrenal insufficiency
  • Aortic stenosis
  • CV disease
  • Cerebrovascular disease
  • Collagen vascular disease
  • SLE
  • Prediabetes or diabetes mellitus
  • Salt or volume depletion
  • Hypercholesterolemia
  • Hypercalcemia
  • Liver cirrhosis
  • Hypertrophic cardiomyopathy with outflow obstruction
  • Unstented unilateral/bilateral renal artery stenosis
  • Parathyroid disease
  • History of allergy or bronchial asthma
  • Patients undergoing major surgery or during anaesthesia
  • Black race
  • Patients undergoing LDL apheresis with dextran sulfate cellulose or desensitization treatment with hymenoptera venom
  • Renal and hepatic impairment
  • Pregnancy
  • Lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Quinapril + Hydrochlorothiazide may interact with the following medicines:

  • Nitrates
  • Vasodilators
  • Diuretics
  • Barbiturates
  • Narcotics
  • Antacids
  • Heparin
  • Sulfamethoxazole/ Trimethoprim
  • K-sparing diuretics
  • K supplements or K-containing salts
  • Tetracycline
  • Rapamycin
  • Racecadotril
  • Vildagliptin
  • COX-2 inhibitors
  • Allopurinol
  • Procainamide
  • Cytostatic and immunosuppressive agents
  • Insulin and oral hypoglycemics agents
  • Norepinephrine
  • Tubocurarine
  • NSAIDS
  • Corticosteroids and ACTH
  • Colestipol and cholestyramine

Potentially fatal: Aliskerin, Sacubitril/Valsartan

This article does not contain all possible drug interactions because it may change how your medications work or increase your risk for serious side effects.  Keep a list of all the products you use and consult it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins. 

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details. 

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking. 

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Symptoms of overdose may include the following:

  • Severe hypotension 
  • Electrolyte depletion
  • Dehydration

Seek medical help immediately. 

Available Brands:

  • Accuzide

Related Articles

ULTRAVIST

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultravist is used in the following conditions: Radiographic Imaging: Iopromide injection is utilized to enhance the [...]

ULTRAMOX

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultramox is used in the following conditions: Respiratory Infections: Amoxicillin is often used to treat respiratory [...]

ULTRALIV

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultraliv is used in the following conditions: Carnitine Orotate: Carnitine orotate is a combination of L-carnitine [...]