Precautions
Before taking alogliptin/pioglitazone, tell your doctor promptly if you have the following medical condition:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness) caused by another DPP-4 inhibitor (eg, saxagliptin)
- if you have a history of liver or kidney problems, abnormal liver function tests, heart problems (eg, congestive heart failure [CHF]), inflammation of the pancreas (pancreatitis), stones in your gallbladder (gallstones), bladder cancer, or eye or vision problems (eg, macular edema)
- if you have a history of bone fracture, low calcium intake, or weak bones (eg, osteoporosis)
- if you have swelling problems (edema)
- if you have a history of alcohol abuse
Interactions
Pioglitazone-Alogliptin can interact with other medications, herbs, or vitamins you might be taking. It is important to notify your doctor if you’re taking any or planning to take other drug. Talk to your doctor or pharmacist if you want to know more about these interactions.