Watsons Health

PILOCARPINE

Pilocarpine is a drug that is known as a tertiary amine parasympathomimetic that leads to the stimulation of the cholinergic receptors in the eyes, causing pupillary constriction, spasm of convenience and decrease of intraocular pressure (IOP). It can also relieve increased pressure in the mouth. It may be used for angle closure glaucoma before surgery, as well as open angle glaucoma. It brings about pupil constriction in the eyes.

Uses

Pilocarpine is used to treat the following:

  • Symptoms of dry mouth due to a certain immune disease (Sjogren’s syndrome) or from saliva gland damage due to radiation treatments of the head/neck for cancer
  • Glaucoma

Warnings

Do not give Pilocarpine to people with the following conditions:

  • Acute inflammatory disease of the anterior segment
  • Cardiorenal disease
  • Uncontrolled asthma
  • COPD and other chronic diseases at risk for cholinergic agonists

Side Effects

Pilocarpine may have the following side effects:

  • Blurred vision
  • Brow ache
  • Ciliary spasm
  • Influenza-like symptoms
  • Rhinitis

Conjunctivitis

Precautions

Take extra caution in patients with the following medical conditions:

  • History of retinal detachment
  • Corneal or conjunctival damage
  • Cognitive or psychiatric disorders
  • Epilepsy
  • Pregnancy and lactation

 

Interactions:

Pilocarpine may interact with the following medicines:

  • Beta-blockers
  • Miotics
  • Parasympathomimetic drugs

Overdose & Brands

Symptoms of overdose include the following:

  • Abdominal cramps
  • Diarrhea
  • Nausea
  • Vomiting
  • Twitching
  • Fasciculations
  • Generalized weakness

Seek medical help immediately.

Available Brand:

  • Isopto Carpine

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