PENTAZOCINE + ACETAMINOPHEN

Do not use this drug:

• If you are allergic to any ingredient in Acetaminophen/Pentazocine.
• If you have a history of substance dependence or abuse.
• If you are taking sodium oxybate (GHB) or other drugs that contain Acetaminophen.

Common side effects may include:

• Constipation
• Dizziness
• Drowsiness
• Light-Headedness
• Nausea
• Sweating

Notify your doctor promptly if any of these symptoms persist or worsen.

Your doctor may have prescribed this medication because he or she judged that the benefit to you is greater than the risk of side effects.

Serious side effects may include:

• Severe Allergic Reactions (Rash; Hives; Itching; Difficulty Breathing; Tightness in the Chest; Swelling of the Mouth, Face, Lips, Throat, or Tongue)
• Blistered, Red, Peeling, or Swollen Skin
• Confusion
• Disorientation
• Fainting
• Fast Heartbeat
• Fever
• Chills
• Persistent Sore Throat
• Hallucinations
• Mental or Mood Changes (eg, Depression, Exaggerated Sense of Well-Being)
• Seizures
• Severe or Persistent Drowsiness, Dizziness, Light-Headedness, or Headache
• Slow or Shallow Breathing
• Symptoms of Liver Problems (eg, Dark Urine, Loss of Appetite, Pale Stools, Severe Stomach Pain, Yellowing of the Skin or Eyes)
• Tremor
• Trouble Sleeping
• Trouble Urinating
• Vision Problems (eg, Blurred Vision)
• Vomiting
• Weakness

Seek immediate medical attention if you experience any of these serious side effects.

Precautions

Before taking this drug, tell your doctor or pharmacist:

• If you are allergic to it or if you have any other allergies.
• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• Your medical condition such as:
  • Poor Health
  • Low Blood Oxygen Levels
  • High Blood Carbon Dioxide Levels
  • Stomach Pain
  • Severe or Persistent Diarrhea Caused by Antibiotic Use (Pseudomembranous Colitis)
• Your medical history, especially of:
  • Head Injury
  • Growths in the Brain (eg, Tumors)
  • Increased Pressure in the Brain
  • Seizures
  • Stomach or Bowel Problems (eg, Blockage, Inflammation, Stomach or Bowel Surgery)
  • Lung or Breathing Problems (eg, Asthma, Chronic Obstructive Pulmonary Disease [COPD])
  • High Carbon Dioxide Levels in the Blood
  • Liver Problems (eg, Hepatitis)
  • Kidney Problems
  • Heart Problems (eg, Cor Pulmonale)
  • A Recent Heart Attack
  • High Blood Pressure
  • The Blood Disease Porphyria
  • Thyroid Problems
  • Adrenal Gland Problems (eg, Addison Disease)
  • An Enlarged Prostate or Benign Prostatic Hypertrophy (BPH)
  • Gallbladder Problems
  • Inflammation of the Pancreas (Pancreatitis)
  • Urinary Blockage or Trouble Urinating
  • Curvature of the Spine (Scoliosis)
  • Mental or Mood Problems
  • Suicidal Thoughts or Actions
  • Drug or Alcohol Abuse or Dependence

Interactions

Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

Possible interactions with this drug are:

• Anticholinergic Medicines (Oxybutynin, Scopolamine)
• Phenothiazines (Chlorpromazine)
• Sleep Medicines (Zolpidem)
• Sodium Oxybate (GHB)
• Other Narcotic Medicines (Oxycodone)
• Anticoagulants (Warfarin)
• Maois (Phenelzine)
• Sibutramine
• Naltrexone
• Methadone or other Narcotic Medicines (Oxycodone)

Medicines that may Harm the Liver (Methotrexate, Ketoconazole, Isoniazid, Certain Medicines for HIV Infection)

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

• Anxiety
• Burning, Numbness, or Tingling
• Confusion
• Excessive Sweating
• Extreme Fatigue
• Fainting
• Fast Heartbeat
• Hallucinations
• Loss of Consciousness
• Nausea
• Nightmares
• Seizures
• Slow or Shallow Breathing
• Sluggishness
• Symptoms of Liver Problems (eg, Dark Urine, Loss of Appetite, Right-Sided Stomach Pain, Yellowing of the Eyes or Skin)
• Unusual Bruising or Bleeding
• Unusual Drowsiness, Dizziness, Headache, or Light-Headedness
• Unusual Thoughts
• Vomiting