OXYTOCIN + ERGOMETRINE

Oxytocin + Ergometrine operates on the uterus by a variety of methods, all of which are complementary. The cyclic nonapeptide oxytocin stimulates G-protein-coupled receptors in the uterus, causing a rise in intracellular Ca levels in uterine myofibrils and thereby encouraging uterine contractions.

Ergometrine, an ergot alkaloid, produces a persistent tonic uterine effect by acting on the 5-HT2 and -adrenergic receptors.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Oxytocin + Ergometrine is used in the following conditions:

Treatment and prophylaxis of postpartum haemorrhage
Active management of the third stage of labour

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Oxytocin + Ergometrine in people with the following conditions:

Uterine inertia (primary or secondary)
Labor induction
Heart failure
Hypertension that is severe
Pre-eclampsia
Eclampsia
Occlusive vascular disease
Sepsis
Severe hepatic and renal dysfunction
Pregnancy
First or second stage of labor before the delivery of anterior shoulder

Side Effects

Oxytocin + Ergometrine may have the following side effects:

Headache
Cerebrovascular accident
Dyspnea
Abdominal pain
Angioedema
Dizziness
Rash
Hypertension
Hypotension
Angina
Myocardial ischaemia
MI
Anaphylaxis
Chest pain
Bradycardia
Arrhythmia
Nausea
Vomiting

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Hypertensive women (mild to moderate)
Coronary artery disease (CAD)
Long QT syndrome
Raynaud’s syndrome
Renal and hepatic impairment ranging from mild to substantial

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Oxytocin + Ergometrine may interact with the following medicines:

Oxytocin
Ergometrine
Glyceryl trinitrate
Antianginal drugs
Vasoconstrictors
Sympathomimetics
Halothane
Cyclopropane
Isoflurane
Desflurane
Sevoflurane

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or maycause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

Symptoms of overdose may include the following:

Vasospastic reactions
Convulsion
Coma
Nausea
Vomiting
Respiratory depression
Hypotension or hypertension

Seek medical help immediately.

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