OXYBUTYNIN TRANSDERMAL

COMMON BRAND NAME(S): Oxytrol

GENERIC NAME(S): OXYBUTYNIN

 

Description: Oxybutynin exerts direct antispasmodic effect on the smooth muscle especially on the urinary smooth muscle.

Pharmacokinetics:

Absorption: Peak plasma concentrations after 1 hr.

Distribution: Crosses the blood-brain barrier; enters breast milk.

Metabolism: Hepatic: Undergoes first-pass metabolism.

Excretion: Excreted in urine and faeces as metabolites. Elimination half life 2-3 hr.

  • Used for
    • Treatment of overactive bladder by relaxing the muscles in the bladder
      • Improves symptoms such as the inability to control urination (incontinence), feeling that one has to urinate (urgency), and having to go to the bathroom often (frequency).
      • Belongs to the class of drugs known as antispasmodics.
  • Not recommended for use in children younger than 5 years of age. Consult your physician for more details
  • The over-the-counter product should only be used by adult women who have symptoms of overactive bladder for at least 2 months unless otherwise specified by your physician

How to use oxybutynin transdermal

  • If you are self-medicating, read all directions on the product package before taking this medication Always refer to your doctors instructions before taking this medication. Duration and dosage will be determined by your medical condition and its response to the medication. Make sure to take this mediciation in the prescribed amount and time period even after symptoms disappear. Discontinuing the medication before completion of treatment may cause incomplete treatment of condition. If Symptoms persist, consult your doctor
  • One patch to your skin, usually every 3 to 4 days.
  • Remember to remove the old patch before applying a new patch.
  • To prevent skin irritation, apply the new patch to a different areas of skin
    • If the area around the patch becomes red, itchy, or irritated, re-apply onto a new site
  • At least 7 days must have passed before applying patch in the same area
  • Throughly wash and pat dry the area the patch will be applied on
    • Apply the patch to an area of clean, dry, smooth skin on the stomach (abdomen), hips, or buttocks. Press firmly to be sure the patch stays on. Apply to an area of skin that is under clothing and protected from sunlight. Avoid applying the patch on your waistline, as it might loosen or be rubbed off by clothing. Do not apply the patch to oily/red/cut/irritated/broken skin or skin covered with lotion or powder. Do not cut the patch into smaller sizes unless otherwise directed.
  • Swimming and bathing with the patch on are possible but avoid rubbing the patch during these activities
  • Should the patch falls off, reapply it or apply a new patch to a new area and continue on your same schedule
  • Minor side effects (if these symptoms persist or worsen, inform your doctor)
    • Skin redness/itching/irritation at the application site, dry mouth, drowsiness, dizziness, blurred vision, headache, weakness, nausea or constipation
    • To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use a saliva substitute
    • To prevent constipation, have a diet adequate in fiber, keep hydrated, and get adequate exercise
  • Serious side effects (inform your doctor immediately)
    • vision problems (including eye pain), difficulty urinating, signs of kidney infection (such as burning/painful/frequent urination, lower back pain), fast/irregular heartbeat, mental/mood changes (such as confusion, hallucinations), fever, flushed/hot/dry skin, signs of stomach/intestinal blockage (such as severe stomach pain, persistent nausea/vomiting, severe constipation).
  • Severe allergic reactions are rare. Get immediate medical help if you notice the following:
    • Rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing

Precautions:

  • Inform your doctor
    • Allergy to the medication

Medical History of active internal bleeding, blockage/slowed movement of the stomach/intestines (such as gastric retention, paralytic ileus), certain bladder problems (urinary retention, bladder outflow obstruction, stress incontinence), glaucoma (narrow-angle), a certain muscle disease (myasthenia gravis), liver disease, high blood pressure, heart problems (such as coronary artery disease, congestive heart failure, arrhythmias), stomach/intestinal disease (such as acid reflux, hiatal hernia, ulcerative colitis, intestinal atony), kidney disease, loss of mental abilities (dementia), enlarged prostate, overactive thyroid (hyperthyroidism), a certain nervous system disorder (autonomic neuropathy), Parkinson’s disease, signs of a bladder/kidney infection (such as burning/pain when you urinate, fever, pink/bloody urine), signs of diabetes (such as increased thirst, dizziness/fainting, vision changes, change in the amount of urine, wounds that are slow to heal).

  • May cause dizziness or drowsiness
  • May make you sweat less making you more prone to getting heat stroke
  • If you are going to have an MRI test, inform the technicians of the patch as some patches may contain metals that can cause serious burns during an MRI
  • Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, trouble urinating. Drowsiness and confusion can increase the risk of falling.
  • Should be used when there is a clear need during pregnancy. If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.
  • It is not known if this drug passes into breast milk. Before breast-feeding, consult your physician.

 

Interactions:

Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

  • Products that may interact with this medication include:
    • anticholinergic drugs (such as atropine, scopolamine), certain anti-Parkinson’s drugs (such as benztropine, trihexyphenidyl), other antispasmodic drugs (such as dicyclomine, propantheline), belladonna alkaloids, potassium tablets/capsules, pramlintide, oral bisphosphonates (such as alendronate, etidronate).
    • products that cause drowsiness including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine).
  • Double check the labels on all medications you are currently taking especially cough-and-cold products since they may contain drowsiness-causing components

Overdose:

This medication patch may be harmful if chewed or swallowed. If overdose or swallowing is suspected, remove the patch if possible, and contact a poison control center or emergency room immediately.

Missed Dose

If you forget to change a patch on your scheduled time, remove the old patch and apply a new one as soon as you remember

If you are using this product on a regular schedule and forget to change the patch on the right day, remove the old patch and apply a new one as soon as you remember. Resume your usual schedule. Do not increase the dose to compensate for the missed dose.

Storage

  • Room temperature in the original sealed pouch
  • Do not expose to light and moisture
  • Do not store in the bathroom
  • Keep all medications away from pets and children

 

Brands:

Available Brands:

Oxytrol

Driptane [ Abbott ]

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