OSIMERTINIB

Osimertinib is a drug that is used to treat non-small cell lung carcinomas with mutation. It is a third-generation tyrosine kinase inhibitor that affects epidermal growth factors. Osimertinib is utilized to treat non-small cell lung cancers (NSCLC), if the diseased cells are positive for T790M mutation.

Uses

Osimertinib is used in the following:

Locally advanced or metastatic EGFR T790M mutation-positive non-small cell lung cancer (NSCLC) which progressed on or after EGFR TKI therapy

Warning

Do not use Osimertinib in patients with the following conditions:

Hypersensitivity

Side Effects

Osimertinib may have the following side effects:

Shortness of breath even with mild exertion
Fast or pounding heartbeats
Alight-headed feeling, like you might pass out
Swelling
Rapid weight gain
Sudden chest pain or discomfort
Wheezing, dry cough
Feeling short of breath

Precautions

Take extra caution in patients with the following medical conditions:

Discontinue if interstitial lung disease is confirmed or with hold treatment and promptly investigate if worsening of resp symptoms occur
Heart disease
Pregnancy
Lactation
Children
Adolescents less than 18 years

Interactions

Osimertinib may interact with the following medicines:

Phenytoin
Rifampicin
Carbamazepine
Rosuvastatin

Overdose & Brands

If you think you have used Osimertinib more than usual dosage, seek medical help immediately.

Available Brand:

Tagrisso