OSELTAMIVIR

COMMON BRAND NAME(S): Tamiflu

GENERIC NAME(S): OSELTAMIVIR PHOSPHATE

 

Description: Oseltamivir is a prodrug of oseltamivir carboxylate (OC) which prevents the release of viruses from infected host cells

Pharmacokinetics:

Absorption: Readily absorbed from the GI tract (oral).

Distribution: Protein-binding: 3% (carboxylate); 42% (parent drug).

Metabolism: Hepatic; extensively metabolised to oseltamivir carboxylate.

Excretion: Via urine. Half-life: 1-3 hr.

  • Used to treat
    • Symptoms caused by the flu virus (influenza) such as stuffy nose, cough, sore throat, fever/chills, aches, tirednes; shortens the recovery time by 1-2 days.
    • Flu Prevention
  • Minor side effects (if these symptoms persist or worsen, inform your doctor)
    • Nausea and vomiting may occur
  • Serious side effects (inform your doctor immediately)
    • Rarely cause serious mental/mood changes more likely in children. Inform your doctor right away of any signs of unusual behavior, including: confusion, agitation, self-injury.
  • Severe allergic reactions are rare. Get immediate medical help if you notice the following:
    • Rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Precautions:

  • Inform your doctor if you
    • Are allergic to the medication
    • Have a history of kidney disease (including dialysis treatment)
  • If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.
  • Consult your doctor before breast-feeding as this medication passes into breast milk, harmful effects on the baby are unlikely.

 

Interactions:

Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

Inform your physician if you have received flu vaccine in the nose within 2 weeks before treatment with this medication as his medication may lower your protection from flu vaccine given via the nose. At least 2 days after ending treatment with this medication shoould have passed before receiving flu vaccine given in the nose.

Overdose:

If overdose is suspected, contact a poison control center or emergency room immediately.

Notes

Do not share this medication with others.

This medication is not a substitute for the flu vaccine. Consult your doctor about the risks and important benefits of receiving a yearly flu shot to lower your chances of getting the flu.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is within 2 hours of your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

  • Room temperature
  • Do not expose to light and moisture
  • Do not store in the bathroom
  • Keep all medications away from pets and children

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

 

Brands:

Also marketed as:

RiteMED Oseltamivir [ RiteMED ]                                                                                      Tamiflu [ Roche ]

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