ORCIPRENALINE

Orciprenaline is a direct acting sympathomimetic with predominantly β2-adrenoceptor stimulant activity and it has minimal effects on heart rate.

Uses

Orciprenaline is used in the long term management of reversible airways obstruction, acute bronchospasm and bradycardia.

Warnings

Avoid using in patients with cardiac arrhythmias associated with tachycardia.

Side Effects

Orciprenaline may bring about side effects such as the following:

  • Tachycardia
  • Nervousness
  • Increased serum glucose
  • Increased potassium levels
  • Tremor
  • Palpitation
  • Headache
  • Dizziness
  • Insomnia
  • Nausea
  • Vomiting
  • Bad taste
  • Heartburn
  • Xerostomia
  • Trembling
  • Muscle cramps
  • Weakness
  • Coughing
  • Pharyngitis
  • Increased diaphoresis
  • Paradoxical bronchospasm
  • Hypertension
  • Chest pain
  • Angina
  • Drowsiness
  • Diarrhoea
  • Taste change

Precautions

Take precautions in patients with the following conditions:

  • Heart disease (e.g. arrhythmia, hypertension, CHF)
  • Diabetes mellitus
  • Glaucoma
  • Hyperthyroidism
  • Hypokalaemia
  • Seizure disorders
  • Pregnancy and lactation
  • β-blockers e.g. propranolol
  • Inhaled ipratropium
  • MAOIs
  • TCAs
  • Sympathomimetics
  • Halothane

Overdose & Brands

Orciprenaline overdose may bring about symptoms such as the following:

  • Tachycardia
  • Tremor
  • Hypertension
  • Angina
  • Seizures
  • Hypokalaemia

Seek medical treatment immediately

 

Available Brands:

Alupent, Broncodual Compuesto, Silomat Comp, Brondin, and Cosica

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