Olmesartan + Hydrochlorothiazide is a combination drug that is made up of olmesartan, an antihypertensive, and hydrochlorothiazide, a diuretic.
Olmesartan antagonizes the vasoconstricting and aldosterone-secreting effects of angiotensin II by selectively binding to angiotensin II type 1 receptors on smooth muscle cells of the arteriole vasculature, thus causing vasodilation and blood pressure reduction.
Hydrochlorothiazide belongs to the thiazide class of diuretics acting solely at the beginning of the distal tubules. It hastens the release of sodium and chloride ions as well as water through the process of electrolyte reabsorption reduction from the renal tubules.
Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.
The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.
If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.
Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.
If you have any inquiries with regards to information, ask your physician or pharmacist.