HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

OLMESARTAN + HYDROCHLOROTHIAZIDE

Olmesartan + Hydrochlorothiazide is a combination drug that is made up of olmesartan, an antihypertensive, and hydrochlorothiazide, a diuretic.

Olmesartan antagonizes the vasoconstricting and aldosterone-secreting effects of  angiotensin II by selectively binding to angiotensin II type 1 receptors on smooth muscle cells of the arteriole vasculature, thus causing vasodilation and blood pressure reduction.

Hydrochlorothiazide belongs to the thiazide class of diuretics acting solely at the beginning of the distal tubules. It hastens the release of sodium and chloride ions as well as  water through the process of electrolyte reabsorption reduction from the renal tubules.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

  • lmesartan + Hydrochlorothiazide is used in the following conditions:

    This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

  • Do not use Olmesartan + Hydrochlorothiazide in people with the following conditions:
    • Hypersensitivity to olmesartan, hydrochlorothiazide, or sulphonamide-derived drugs
    • Anuria
    • Cholestasis
    • Biliary obstruction
    • Refractory hypokalemia
    • Hypercalcemia
    • Hyponatremia
    • Symptomatic hyperuricemia
    • Severe hepatic and severe renal impairment (CrCl <30 mL/min) impairment
    • Pregnancy and lactation
    • Concomitant use with aliskiren-containing products in patients with diabetes mellitus or renal (GFR <30 mL/min) impairment

Olmesartan + Hydrochlorothiazide may have the following side effects:

  • Angioedema
  • Electrolyte disturbance
  • Sprue-like enteropathy
  • Gout
  • Hypotension
  • Acute transient myopia
  • Acute angle-closure glaucoma
  • Photosensitivity
  • Renal function deterioration
  • Hypersensitivity
  • Aplastic anemia
  • Bone marrow depression
  • Leukopenia
  • Thrombocytopenia
  • Palpitations
  • Nausea
  • Diarrhea
  • Dyspepsia
  • Abdominal pain
  • Vomiting
  • Asthenia
  • Chest pain
  • Fatigue
  • Malaise
  • Peripheral edema
  • Weakness
  • Sialadenitis
  • Increased creatinine phosphokinase
  • Increased SGOT/SGPT
  • Hypercholesterolemia
  • Hypertriglyceridemia
  • Hyperuricemia
  • Arthralgia
  • Back pain
  • Muscle spasm
  • Myalgia
  • Pain in extremity
  • Dizziness
  • Headache
  • Somnolence
  • Postural dizziness
  • Syncope
  • Vertigo
  • Hematuria
  • Erectile dysfunction
  • Upper respiratory infection
  • Cough
  • Angioneurotic edema
  • Eczema
  • Rash
  • Urticaria
  • Orthostatic hypotension

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Aortic/mitral stenosis
  • Obstructive hypertrophic cardiomyopathy
  • Diabetes mellitus
  • Diabetic nephropathy
  • Hypercalcemia
  • Hypercholesterolemia
  • Parathyroid disease
  • Renal artery stenosis
  • SLE
  • Intravascular volume depletion
  • Primary aldosteronism
  • Mild to moderate hepatic or renal impairment

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

 

Interactions

Olmesartan + Hydrochlorothiazide may interact with the following medicines:

  • Lithium
  • NSAIDs
  • Other antihypertensive agents
  • Barbiturates
  • Narcotics
  • Antidepressants
  • Potassium-sparing diuretics
  • Potassiumsupplements
  • Potassium-containing salt substitutes
  • Carbamazepine
  • Colesevelam
  • Antacids
  • Digitalis
  • Skeletal muscle relaxants
  • Fat-soluble vitamins
  • Folate
  • Iron
  • Corticosteroids
  • ACTH
  • Laxatives
  • Cytotoxic agents
  • Pressor amines
  • Beta-blockers
  • Diazoxide
  • Anticholinergic agents
  • Metformin
  • Allopurinol
  • Amantadine
  • Methyldopa
  • Ciclosporin
  • Tetracycline
  • Calcium-containing medicinal products
  • Aliskiren

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you think you have used Olmesartan + Hydrochlorothiazide more than the usual dosage, please seek medical help immediately.

 

Available Brand:

  • Alzor HCT
  • Olmetec Plus

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