HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

Norelgestromin + Ethinylestradiol

Norelgestromin is a  progestogenic compound used for contraception and menopausal hormone therapy. Ethinylestradiol is a synthetic estrogen compound which decreases gonadotropic hormone to prevent ovulation and decreases luteinizing hormone to reduce endometrial vascularization. This combination of contraceptives works by suppressing gonadotropins which thickens the cervical mucus to prevent sperm form travelling into the uterus, preventing changes in the endometrium, thus leading to inhibition of ovulation.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Norelgestromin + Ethinylestradiol is used in the following conditions:

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Norelgestromin + Ethinylestradiol in people with the following conditions:

  • Thrombophlebitis
  • Thromboembolic disorders
  • History of deep vein thromboembolic disorders
  • Cerebrovascular or coronary artery disease
  • Valvular heart disease with complications
  • Severe hypertension
  • Diabetes mellituswith vascular involvement
  • Headaches with focal neurological symptoms
  • Major surgery with prolonged immobilisation
  • Known or suspected carcinoma of the breast or history of breast cancer
  • Carcinoma of the endometrium or other known or suspected estrogen-dependent neoplasia
  • Undiagnosed abnormal genital bleeding
  • Cholestatic jaundice of pregnancy or jaundice with prior hormonal contraceptive use
  • Acute or chronic hepatocellular disease with abnormal liver function
  • Hepatic adenomas or carcinomas
  • Known or suspected pregnancy

Norelgestromin + Ethinylestradiol may have the following side effects:

  • Breast symptoms
  • Headache
  • Application site reaction
  • Nausea
  • Upper respiratory infection
  • Menstrual cramps and abdominal pain
  • Changes in weight
  • Cervical erosion and secretion
  • Diminution in lactation when given immediately postpartum
  • Cholestatic jaundice
  • Migraine
  • Rash (allergic)
  • Mental depression
  • Reduced tolerance to carbohydrates
  • Vaginal candidiasis
  • Changes in corneal curvature
  • Intolerance to contact lenses

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more significant than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A severe allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Women above 35 years oldand/or smokers
  • Hypertension
  • Hypercholesterolemia
  • Morbid obesity
  • Diabetes mellitus

Prior in taking this medicine, tell your physician or pharmacist if you have allergies  or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

 

Interactions

Norelgestromin + Ethinylestradiol may interact with the following medicines:

  • Barbiturates
  • Griseofulvin
  • Rifampicin
  • Phenylbutazone
  • Phenytoin
  • Carbamazepine
  • Felbamate
  • Oxcarbazepine
  • Topiramate
  • Ampicillin
  • HIV protease inhibitors
  • Ciclosporin
  • Prednisolone
  • Theophylline
  • Temazepam
  • Salicylic acid
  • Morphine
  • Clofibric acid

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you think you have used Norelgestromin + Ethinylestradiol more than the usual dosage, please seek medical help immediately.

Symptoms of overdose may include the following:

  • Nausea
  • Vomiting
  • Withdrawal bleeding may occur in females

 

Available Brands:

  • Xulane

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