MIPOMERSEN SODIUM

Mipomersen sodium inhibits the ApoB-100 molecule, a protein that plays a pivotal role in the production of low-density lipoprotein (LDL). It reduces LDL-C by preventing the formation of atherogenic lipoproteins, the particles that carry cholesterol through the bloodstream.

Uses

It is specifically indicated as an adjunct to lipid-lowering medications and diet to reduce low density lipoprotein-cholesterol (LDL-C), apolipoprotein B (apo B), total cholesterol 31 (TC), and non-high density lipoprotein-cholesterol (non-HDL-C) in patients with homozygous familial hypercholesterolemia (HoFH).

Warnings

This medication increases hepatic fat (steatosis). Hepatic steatosis is a risk factor for advanced liver disease, including steatohepatitis and cirrhosis.

Alcohol may increase levels of hepatic fat and induce or exacerbate liver injury. It is recommended that patients taking KYNAMRO should consume no more than one alcoholic drink per day.

Side Effects

Adverse side effects associated with the use of Mipomersen sodium may include:

Injection Site Reactions
Flu-Like Symptoms
Nausea
Headache
Elevations in Serum Transaminases

Precautions

Precautions

Before taking Mipomorsen Sodium, tell your doctor:

If you are allergic to any component of Mipomorsen Sodium or if you have any other allergies.
You medical history especially of liver diseases and alcohol abuse.
If you are pregnant or breastfeeding.

Interactions

Some medicines may interact with this drug. Tell your health care provider if you are taking any other medicines including prescription and non-prescription or herbal medicines.

Overdose & Brands

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Available brand/s:

Acifox
Aefox
Aglophin