HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

METFORMIN + VILDAGLIPTIN

Metformin + Vildagliptin is a combination drug that is made up of Metformin and Vildagliptin. Metformin is a biguanide antidiabetic drug that diminishes hepatic glucose creation by limiting gluconeogenesis and glycogenolysis. It also improves use and take-up of glucose by increasing insulin resistance, and defers intestinal glucose absorption. Vildagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4), subsequently increasing glucagon-like peptide-1 (GLP-1) and glucose-subordinate insulinotropic polypeptide (GIP) levels. This upgrades glucose-dependent insulin secretion and decreases glucagon production.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Metformin + Vildagliptin is used in the following conditions:

  • Type 2 diabetes mellitus

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Metformin + Vildagliptin in people with the following conditions:

  • Lactic acidosis
  • Diabetic ketoacidosis
  • Dehydration
  • Severe infection
  • Shock
  • Cardiac or respiratoryfailure
  • Recent heart attack
  • Undergoing surgery
  • Acute alcohol intoxication
  • Lactation
  • Severe hepatic and renal impairment
  • Intravascular administrationof iodinated contrast agents

Metformin + Vildagliptin may have the following side effects:

  • Dehydration
  • Acute pancreatitis
  • Bullous and exfoliative skin lesions
  • Decreased vitamin B12 levels
  • Hypoglycemia
  • Hepatitis
  • Dizziness
  • Tremor
  • Headache
  • Fatigue
  • Diarrhea
  • Hyperhidrosis
  • Lactic acidosis

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist

Take extra caution in patients with the following medical conditions:

  • Patient with history of acute pancreatitis
  • Mild to moderate renal impairment
  • Pregnancy
  • Not intended for the treatment of type 1 diabetes mellitusand diabetic ketoacidosis

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Metformin + Vildagliptin may interact with the following medicines:

  • Cimetidine
  • ACEinhibitors
  • Angiotension receptor antagonists
  • Diuretics
  • NSAIDs
  • Thiazide diuretics
  • Corticosteroids
  • Phenothiazines
  • Thyroid products
  • Oral contraceptives
  • Sympathomimetics
  • Phenytoin
  • Niacin
  • Calciumchannel blockers
  • Isoniazid
  • Intravascular administrationof iodinated contrast agents

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

  • Nausea
  • Vomiting
  • Epigastric pain
  • Hypotension
  • Tachycardia
  • Tachypnea
  • Arrhythmia
  • Renal insufficiency
  • Coma
  • Cardiac arrest

 

Available Brands:

  • Galvusmet

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