Mayaro virus infection is transmitted from person to person by the bite of a mosquito that is already infected. Parts of Central America, South America, and the Caribbean have been infected with the virus. People who live near woods or visit tropical forests are more at risk of illness. Preventing mosquito bites is the most effective strategy to protect yourself against Mayaro virus sickness. When going outside, use an EPA-registered bug repellent and dress in long sleeves and pants. The Mayaro virus is transmitted to humans by the bite of an infected mosquito.