LYMPHOMA OF THE BRAIN

Primary lymphoma of the brain is cancer of the white blood cells that starts in the brain. The cause of primary brain lymphoma is not known. However, people with a weakened immune system are at high risk for this disease. It is more common in people ages 45 to 70.

Primary lymphoma of the brain may be linked to Epstein-Barr Virus (EBV), especially in people with HIV/AIDS. EBV is the virus that causes mononucleosis.

Symptoms of primary brain lymphoma may include any of the following:

  • Changes in Speech or Vision
  • Confusion or Hallucinations
  • Fever
  • Headaches or Seizures
  • Leaning to One Side When Walking
  • Weakness in Hands or Loss of Coordination
  • Numbness to Hot, Cold, and Pain
  • Personality Changes
  • Weight Loss

Diagnosis

To help diagnose primary lymphoma of the brain, the following tests may be done:

  • Biopsy of the brain
  • Head CT scan or MRI
  • Spinal Tap (Lumbar Puncture)

 

Treatment

Primary lymphoma of the brain is usually first treated with medicines called corticosteroids to control swelling and improve symptoms. Treatment may include:

  • Chemotherapy. This is the main treatment of the disease. Younger people may receive high-dose chemotherapy, possibly followed by an autologous stem cell transplant.
  • Radiation therapy. This is done to the whole brain. It may be perform after chemotherapy.
  • Boosting the immune system, such as in those with HIV, may also be tried.

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