LORAZEPAM: Uses,Warnings, Side Effects,Prescription and Dosage


Lorazepam is a short acting benzodiazepine. It increases neuronal membrane permeability to chloride ions by attaching to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron within the central nervous system, including the limbic system and reticular formation. This also enhances GABA-blocking effects, leading to hyperpolarization and stabilization.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Lorazepam is used in the following conditions:

  • Status epilepticus
  • Premedication in surgery
  • Anxiety
  • Insomnia associated with anxiety
  • Acute anxiety

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

  • Do not use Lorazepam in people with the following conditions:
    • Patient with acute angle-closure glaucoma
    • Sleep apnea syndrome
    • Severe respiratory insufficiency except during mechanical ventilation
    • Severe hepatic impairment

Lorazepam may have the following side effects:

  • Sedation
  • Drowsiness
  • Ataxia
  • Dizziness
  • Confusion
  • Depression
  • Unmasking of depression
  • Hypotension
  • Fatigue
  • Muscle weakness
  • Asthenia
  • Transient anterograde amnesia or memory impairment
  • Changes in vital signs
  • Thrombocytopenia
  • Agranulocytosis
  • Pancytopenia
  • Hyponatraemia
  • Disinhibition
  • Euphoria
  • Suicidal ideation
  • Nausea
  • Constipation
  • Change in libido
  • Impotence
  • Decreased orgasm
  • Increase in bilirubin, liver transaminases or alkaline phosphatase
  • Respiratory depression

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Patient with compromised pulmonary function (decreased reserve)
  • Myasthenia gravis
  • Cardiovascularor cerebrovascular disease
  • Impaired gag reflex
  • At risk of falls
  • Patient with history of alcohol or drug abuse and those with personality disorders
  • Primary depressive or psychotic disorders
  • Should not be administered by intra-arterial injection
  • Avoid abrupt withdrawal
  • Renal and mild to moderate hepatic impairment
  • Elderly or debilitated patients
  • Children
  • Pregnancy and lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.



Lorazepam may interact with the following medicines:

  • Drugs that affect the CNS (e.g. barbiturates, phenothiazines, antidepressants, MAOIs)
  • Scopolamine
  • Caffeine
  • Theophylline
  • Aminophylline
  • Sodium valproate
  • Probenecid

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you think you have used Lorazepam more than the usual dosage, please seek medical help immediately.

You may exhibit the following symptoms in the event of an overdose:

  • Drowsiness
  • Mental confusion
  • Lethargy
  • Ataxia
  • Hypotension
  • Hypotonia
  • Respiratory or cv depression
  • Coma
  • Death


Available Brands:

  • Ativan
  • Lorazepam Intensol


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