Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.

This medication is used on the skin to stop itching and pain from certain skin conditions (e.g., scrapes, minor burns, eczema, insect bites) and to treat minor discomfort and itching caused by hemorrhoids and certain other problems of the genital/anal area (e.g., anal fissures, itching around the vagina/rectum).

Never apply to inflamed or injured skin. Do not give to patients with hypovolemia (low blood volume), complete heart block (a disorder in the heart’s electrical conduction system), Adam-Stokes syndrome (abnormal heart rhythm resulting in fainting and loss of consciousness), and Wolff-Parkinson-White syndrome (a condition in which there is an extra electrical pathway in the heart resulting in rapid heart rate).

Temporary redness, stinging, and swelling may occur at the application site. If these effects persist or worsen, notify your doctor.


Before using lidocaine, tell your doctor or pharmacist if you are allergic to it; or to other amide type anesthetics (e.g., bupivacaine, prilocaine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.



May increase serum levels w/ cimetidine and propranolol. Increased risk of cardiac depression with beta blockers and other anti-arrhythmics. Additive cardiac effects with intravenous phenytoin. Hypokalemia caused by acetazolamide, loop diuretics and thiazides may dampen effect of lidocaine. Dose requirements may be increased with long-term use of phenytoin and other enzyme-inducers. Decreased levels w/ St John’s wort.

This medicine may be harmful if inhaled or swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, bring the victim to the hospital immediately.


Available brands:

  • Elin Lidocaine Hydrochloride (Elin)
  • Lignopad (Mundipharma)
  • Locaine (Shreechem)
  • Phil Pharmawealth/Atlantic Lidocaine (Atlantic Lab)
  • Xylocaine (AstraZeneca)

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