LEVORPHANOL - Watsons Health

LEVORPHANOL

Levorphanol is a narcotic analgesic that acts in the brain and spinal cord to decrease the feeling of pain.

This medication is used to treat or prevent moderate to severe pain like before surgery. This medication may also be used in other conditions to be determined by your doctor.

Do not use this drug:

  • If you are allergic to any ingredient in Levorphanol or similar medicines (eg, Morphine)
  • If you are taking a monoamine oxidase (MAO) inhibitor (eg, Phenelzine), a narcotic agonist/antagonist medicine (eg, Pentazocine), or Sodium Oxybate (GHB)
  • If you are having certain types of surgery (eg, biliary surgery)
  • If you are having an asthma attack, have severe asthma, or have severe diarrhea due to antibiotic use

Common side effects may include:

  • Altered Mood and Thoughts
  • Constipation
  • Dizziness
  • Drowsiness
  • Flushing
  • Nausea
  • Reaction or Pain at the Injection Site
  • Vomiting

Notify your doctor promptly if any of these symptoms persist or worsen.

Your doctor may have prescribed this medication because he or she judged that the benefit to you is greater than the risk of side effects.

Serious side effects may include:

  • Severe Allergic Reactions (Rash; Hives; Difficulty Breathing; Tightness in the Chest; Swelling of the Mouth, Face, Lips, or Tongue)
  • Depression
  • Difficulty Urinating
  • Fainting
  • Fast, Slow, or Irregular Heartbeat
  • Itching
  • Seizures

Seek immediate medical attention if you experience any of these serious side effects.

Precautions

Before taking this drug, tell your doctor or pharmacist:

  • If you are pregnant, planning to become pregnant, or are breast-feeding.
  • If you are allergic to it or if you have any other allergies.
  • If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
  • If you have a history of:
    • Prostate Problems
    • Seizures
    • Heart Problems or a Recent Heart Attack
    • Kidney Problems
    • Liver Disease
    • An Underactive Thyroid
    • Severe Inflammatory Bowel Disease
    • Lung Problems
    • Asthma
    • A Head Injury or Increased Pressure within the Head
    • A Brain Tumor
    • Trouble Urinating
    • Low Blood Pressure
    • Mental or Mood Problems or Suicidal Thoughts
    • Substnace Abuse or Dependence
  • If you will be having surgery on the stomach, intestines, liver, or gallbladder

 

Interactions

Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

 

Possible interactions with this drug are:

  • Cimetidine
  • MAO inhibitors (eg, Phenelzine)
  • Sodium Oxybate (GHB)
  • Naltrexone or Narcotic Agonist/Antagonists (eg, Pentazocine)
  • Antihistamines (eg, Diphenhydramine)
  • Barbiturates (eg, Phenobarbital)
  • Muscle Relaxants (eg, Methocarbamol)
  • Other Narcotic Pain Medicines (eg, Codeine)
  • Phenothiazines (eg, Chlorpromazine)
  • Sleeping Medicines (eg, Zolpidem)
  • Tricyclic Antidepressants (eg, Amitriptyline)

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

  • Cold and Clammy Skin
  • Deep Sleep
  • Dizziness
  • Drowsiness
  • Lightheadedness
  • Slowed Breathing
  • Slowed Heartbeat

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