LEVONORGESTREL + ETHINYLESTRADIOL- Uses, Warnings,Precautions, Overdose and Brands


Levonorgestrel + Ethinylestradiol is a combination drug that is made up of levonorgestrel and ethinylestradiol. It is a hormonal contraceptive that represses ovulation by regulating the pituitary secretion of gonadotrophins, luteinizing hormone and follicle-stimulating hormone through a negative feedback loop. This drug diminishes sperm penetration if ovulation occurs by adjusting cervical bodily fluid; then causes changes in the endometrium which lessen the danger of nidation and may change the tubal transport of eggs through the fallopian tubes. Taking this drug can increase the risk of blood clots, stroke, and heart attacks. One may have more risks if she has high blood pressure, diabetes and high cholesterol and if she is overweight. You can be at high risk for stroke or blood clots in the first year of taking the said pill. Smoking can also cause you to have a higher risk of thromboembolism.

Levonorgestrel + Ethinylestradiol is used in the following conditions:

  • Contraception

Do not use Levonorgestrel + Ethinylestradiol in people with the following conditions:

  • Pregnancy
  • Undiagnosed vaginal bleeding
  • Severe arterial disease
  • Liver adenoma
  • History of breast cancer
  • Diabetes complications
  • History of hemolytic uremic syndrome
  • Breastfeeding during the first six months after delivery

Levonorgestrel + Ethinylestradiol may have the following side effects:

  • Menstrual irregularities
  • Gynaecomastia
  • Depression
  • Haematologic disorders
  • Cholestatic jaundice
  • Increased risk in breast cancer
  • Cortisol
  • May affect serum triglyceride and lipoprotein levels
  • Retinal vascular thrombosis
  • Liver tumors
  • Increased risk of thromboembolism

Take extra caution in patients with the following medical conditions:

  • Sex-steroid dependent cancer
  • Past ectopic pregnancy
  • Functional ovarian cysts
  • Active liver disease
  • Recurrent cholestatic jaundice
  • History of heartor kidney impairment
  • Diabetes mellitus
  • Asthma
  • Familial defects of lipoprotein metabolism
  • Preexisting uterine problems



Levonorgestrel + Ethinylestradiol may interact with the following medicines:

  • Aminoglutethimide
  • Carbamazepine
  • Nafcillin
  • Nevirapine
  • Atazanavir
  • Nelfinavir
  • Phenobarbital
  • Phenytoin
  • Lamotrigine
  • Rifamycins
  • Griseofulvin
  • Ampicillin
  • Tetracycline
  • Alprazolam
  • Chlordiazepoxide
  • Diazepam

If you think you have used Levonorgestrel + Ethinylestradiol more than the usual dosage, please seek medical help immediately.

Available Brands:

  • Femme
  • Lady
  • Minipil
  • Nordette
  • Protec
  • Logynon
  • Trinordiol

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