Description: Ketorolac reversibly inhibits cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, which helps to decrease swelling, pain, or fever.

  • Short-term treatment of moderate to severe pain in adults.

How to use:

  • Always refer to your doctors instructions before taking this medication. Duration and dosage will be determined by your medical condition and its response to the medication. Make sure to take this medication in the prescribed amount and time period even after symptoms disappear. Discontinuing the medication before completion of treatment may cause incomplete treatment of condition. If Symptoms persist, consult your doctor.
  • Taken by mouth; With or without food; usually every 4-6 hours a day with a full glass of water or as directed by your physician.

Minor side effects (if these symptoms persist or worsen, inform your doctor)

  • Upset stomach, nausea, vomiting, constipation, diarrhea, gas, dizziness, or drowsiness.

Serious side effects (inform your doctor immediately)

  • Fainting, fast/pounding heartbeat, hearing changes (such as ringing in the ears), mental/mood changes (such as confusion, depression), persistent/severe headache, stomach pain, sudden/unexplained weight gain, swelling of the hands or feet, vision changes (such as blurred vision), unusual tiredness, easy bruising/bleeding, change in amount of urine, signs of infection (such as fever, chills, persistent sore throat), symptoms of meningitis (such as unexplained stiff neck, fever).
  • May rarely cause serious (possibly fatal) liver disease. Seek immediate medical attention if you have any symptoms of liver damage, including: dark urine, stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin.

Severe allergic reactions are rare. Get immediate medical help if you notice the following:

  • Rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.


  • Inform your doctor.
    • Allergy to the medication or to aspirin or other nonsteroidal anti-inflammatory drugs-NSAIDs (such as ibuprofen, naproxen, celecoxib) or any allergies.
    • Medical History of asthma (including a history of worsening breathing after taking aspirin or other NSAIDs), bleeding or clotting problems, blood disorders (such as anemia), heart disease (such as previous heart attack), high blood pressure, liver disease, growths in the nose (nasal polyps), throat/stomach/intestinal problems (such as bleeding, heartburn, ulcers), stroke, swelling of the ankles/feet/hands.
  • May cause kidney problems. Drink plenty of fluids to keep hydrated and inform your doctor of any changes in amount of urine.
  • May cause dizziness or drowsiness. Limit alcohol intake.
  • May cause stomach/intestinal bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information.
  • May cause light sensitivity (photosensitivity).
    • Avoid prolonged sun exposure, tanning booths or sunlamps.
    • Sunscreen and protective clothing are recommended when outdoors.
  • Should only be used when there is a clear need during pregnancy as it may harm an unborn baby. If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.
  • Consult your doctor before breast-feeding as this medication passes into breast milk and may cause unwanted effects on your baby.



Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

  • Products that may interact with this medication include:
    • aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as losartan, valsartan), lithium, methotrexate, probenecid, corticosteroids (such as prednisone), other medications that may affect the kidneys (including cidofovir, “water pills”/diuretics such as furosemide), anti-platelet drugs such as clopidogrel, “blood thinners” such as dabigatran/enoxaparin/warfarin, among others.
  • Double check all the labels of the medications you are currently taking as many drugs contain pain relievers/fever reducers such as aspirin, NSAIDs such as celecoxib, ibuprofen, ketorolac that may increase your risk of side effects.
  • If your doctor prescribed you low dose aspirin, continue to take it unless you are told otherwise.


If overdose is suspected, contact a poison control center or emergency room immediately.

Symptoms of overdose may include:

  • severe stomach pain, vomit that looks like coffee grounds, extreme drowsiness, slow/shallow breathing.

Missed Dose: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and as soon as you remember, take a regular dose or if the time of the next dose is near, wait for it before taking another dose and resume your usual schedule. Do not increase the dose to compensate for the missed dose.


  • Room temperature between 15-30 degrees C
  • Do not expose to light and moisture
  • Do not store in the bathroom
  • Keep all medications away from pets and children



Available Brands

  • Eurolac [ Renata ]
  • Ketero [ Akums Drug ]
  • Ketobet [ Akums Drug ]
  • Ketodol [ Taiwan Biotech ]
  • Ketomed [ Medhaus ]
  • Ketovex [ Mount Mettur ]
  • Ketral [ Oboi ]
  • Kortezor [ Biomedis ]
  • Marolac [ ACME ]
  • Medlac [ Medica Korea ]
  • Remopain [ Gracio Med ]
  • Rotoket [ Medica Korea ]
  • Teromac [ Huons ]
  • Toramed [ Biolink Pharma ]
  • Torotas [ Cooper Pharma ]
  • Tral [ IBN Sina ]
  • Xevolac [ Prosweal Healthcare ]
  • Zirolac [ Union Korea Pharm ]

Also marketed as

  • Acular [ Allergan ]
  • Alore [ Akums Drug ]
  • Arvolac [ VitaPure ]
  • Dintolac [ DNBG Pharma ]
  • Duopharma Ketorolac Trometamol [ Duopharma (M) Sdn Bhd ]
  • Dyrolac [ Yung Shin ]
  • Inco [ Siu Guan Chem ]
  • Ketanov [ Sel-J Pharma ]
  • Ketlac [ Akums Drug ]
  • Keto [ Yung Shin ]
  • Oradol [ Aristopharma ]
  • Togesic [ Sel-J Pharma ]

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