JANUVIA

JANUVIA or SITAGLIPTIN PHOSPATE is a potent and otrally-active drug used for the inhibition of DPP-4 enzyme activity for a 24-hour period for patients with type 2 diabetes. This results in a 2- to 3-fold increase in the circulating levels of active GLP-1 and GIP, increased plasma levels of insulin and C-peptide, decreased glucagon concentrations, reduced fasting glucose, and reduced glucose excursion following an oral glucose load or a meal,

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

Your physician’s medication dose is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage; take it regularly or as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. Take it at a fixed daily time to make you remember it better.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries regarding information, ask your physician or pharmacist.

Uses

JANUVIA is used in the following conditions:

Januvia is used in patients with type 2 diabetes mellitus.

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use JANUVIA in people with the following conditions:

Hypersensitivity

Side Effects

JANUVIA may have the following side effects:

Headache
Urticaria
Nausea
Flatulence
Upper respiratory tract infection
Flu
Dyspepsia
Myalgia
Abdominal pain
Angioedema
Acute pancreatitis
Rash
Vomiting
Pruritus
Pemphigoid
Peripheral edema
Back pain
Arthralgia
Anaphylaxis
Constipation
Cutaneous vasculitis
Hypoglycemia
Diarrhea
Fungal skin infection
Pain in extremity
Nasopharyngitis

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling, or swelling of the face or tongue or throat, dizziness, or difficulty breathing.

This is not a complete list of side effects. Contact your physician or pharmacist if you see other effects not recorded above.

Precautions

Take extra caution in patients with the following medical conditions:

Patients with type 1 diabetes or diabetic ketoacidosis
Anaphylaxis
Angioedema
Exfoliative skin conditions, including Stevens-Johnson syndrome
Januvia in pediatric patients under 18 years has not been established.

Before taking this medicine, tell your physician or pharmacist if you are allergic to it or if you have some other hypersensitivities. This drug may contain inert ingredients, which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

JANUVIA may interact with the following medicines:

Cholesterol-lowering agents (e.g., statins, fibrates, ezetimibe),
Anti-platelet agents (e.g., clopidogrel),
Antihypertensives (e.g., ACE inhibitors, angiotensin receptor blockers, beta-blockers, calcium channel blockers, hydrochlorothiazide),
Analgesics
Non-steroidal anti-inflammatory agents (e.g., naproxen, diclofenac, celecoxib),
Anti-depressants (e.g., bupropion, fluoxetine, sertraline), antihistamines (e.g., cetirizine),
Proton-pump inhibitors (e.g., omeprazole, lansoprazole),
Medications for erectile dysfunction (e.g., sildenafil)

Inform your physician about the drugs you take, including over-the-counter medications, prescribed drugs, supplements, and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you simultaneously consume different medications or herbal products. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you use without your physician’s advice.

Overdose & Brands

Symptoms of overdose may include the following:

Upper respiratory infection
Stuffy or runny nose
Sore throat
Headache
Stomach upset
Diarrhea
Swelling of the hands or legs

Seek medical help immediately.

Available Brands:

Sitagliptin