Ivacaftor is a potentiator of CFTR protein that enhances the transport of CFTR mutated protein across the membrane by chloride ion. This leads to better control of the absorption of salt and water and secretions in different lung and gastrointestinal tract tissues. Tezacaftor is a protein corrector selective cystic fibrosis transmembrane conductance regulator (CFTR) that enhances the transport of chloride ions by facilitating cellular processing and trafficking, including F508del-CFTR, of normal and multiple mutant types of CFTR.
Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.
The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.
If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.
Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.
