IMIPRAMINE - Watsons Health

IMIPRAMINE

This drug belongs to a class of medications called tricyclic antidepressants that works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) in the brain. For bed-wetting, Imipramine may work by blocking the effect of a certain natural substance (acetylcholine) on the bladder.

Imipramine is used to treat depression. It is also used to prevent bedwetting in children.

Do not use this medication if:

  • You are allergic to any ingredient in Imipramine
  • You have taken linezolid or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
  • You are recovering from a recent heart attack

If any of these apply to you, contact your doctor or health care provider right away.

Antidepressants may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults. Talk with the patient’s doctor to be sure that the benefits of using Imipramine outweigh the risks.

Side effects of this drug include:

  • Nausea
  • Drowsiness
  • Weakness Or Tiredness
  • Excitement Or Anxiety
  • Nightmares
  • Dry Mouth
  • Skin More Sensitive To Sunlight Than Usual
  • Changes In Appetite Or Weight
  • Constipation
  • Difficulty Urinating
  • Frequent Urination
  • Changes In Sex Drive Or Ability
  • Excessive Sweating

Tell your doctor promptly if any of these effects persist or worsen.

Some side effects can be serious. If any of these apply to you, contact your doctor or health care provider right away.

  • Jaw, Neck, And Back Muscle Spasms
  • Slow Or Difficult Speech
  • Shuffling Walk
  • Uncontrollable Shaking Of A Part Of The Body
  • Fever, Sore Throat, Or Other Signs Of Infection
  • Difficulty Breathing Or Swallowing
  • Severe Rash
  • Yellowing Of The Skin Or Eyes
  • Irregular Heartbeat

Precautions

Before using Imipramine, tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • If you are pregnant, planning to become pregnant, or are breast-feeding
  • If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • If you have allergies to medicines, foods, or other substances
  • If you drink alcohol or have a history of alcohol abuse
  • If you take thyroid medicine or you have a history of an overactive thyroid, glaucoma or increased pressure in the eye, heart problems, kidney or liver problems, diabetes, seizures, the blood disease porphyria, or difficulty urinating
  • If you have a history of suicidal thoughts or behavior, bipolar disorder, or any other mental disorders; you are undergoing electroshock therapy; or you are scheduled to have any surgery
  • If you are taking a medicine that contains methylene blue

 

Interactions

Drug interactions may interfere with how your medication works. Tell your doctor about all your medications and any you start or stop using during treatment with Imipramine.

Some products that may interact with this drug including:

  • Anticholinergics (E.G., Atropine, Belladonna Alkaloids, Scopolamine, Drugs For Parkinson’s Disease Such As Benztropine)
  • Certain Drugs For High Blood Pressure (E.G., Clonidine, Guanadrel, Guanethidine, Reserpine)
  • Digoxin
  • Disopyramide
  • Thyroid Supplements
  • Valproic Acid

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing. Symptoms of overdose may include:

  • severe dizziness
  • fast/irregular heartbeat
  • fainting
  • hallucinations
  • seizures

 

Available brand:

  • Imipramine

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