Imidapril belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors, which help relax blood vessels. ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance in your body that narrows your blood vessels and releases hormones that can raise your blood pressure. This narrowing can cause high blood pressure and force your heart to work harder.

Treatment of high blood pressure (hypertension).

Do not give quinapril to pregnant women and persons with history of angioedema related to previous ACE inhibitor treatment. Angioedema is the rapid edema, or swelling, of the area beneath the skin or mucosa. It is normally an allergic reaction, but can also be hereditary. Do not give to patients with diabetes and kidney impairment who are taking the anti-hypertension drug, aliskiren.

Dizziness, lightheadedness, or tiredness may occur as your body adjusts to the medication. Dry cough, nausea, or vomiting may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.


Give with caution to patients with renal artery stenosis; collagen vascular disease, heart failure; at risk for hypotension (e.g. volume-depleted patients); kidney and liver impairment; and lactating women.



Marked hypotension with diuretics, other antihypertensives, and vasodilators, TCAs, neuroleptics. Increases blood potassium level with potassium-sparing diuretics, potassium supplements, and potassium-containing salt substitutes. Reduced antihypertensive effects or additive liver-damaging effects w/ NSAIDs, rifampicin, sympathomimetics. Increased lithium levels and toxicity. May cause nitritoid reactions with injectable gold (sodium aurothiomalate).

Symptoms of overdose include severe hypotension, bradycardia, shock, stupor, electrolyte disturbances and renal failure. If overdose is suspected, bring the victim to the hospital immediately.


Available brands:

  • Norten (LRI)
  • Vascor (Therapharma)

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