IGA NEPHROPATHY

IGA NEPHROPATHY

IgA Nephropathy is a kidney illness caused by a build-up of immunoglobulin A (IgA) in the kidneys. IgA is often the first line of defense in protecting our body from infections. However, when it accumulates in the kidney, it may result in inflammation. This may later on interfere with the blood filtration process of the kidney.

The exact cause of this disease is still undetermined. However, experts speculate that this disease may be caused by genetics, existing liver diseases, or other bacterial infections.

Furthermore, this condition usually develops slowly over time. Nevertheless, the progression of the disease will still vary, depending on the patient. For example, some people may have blood in their pee without any other complications, while others may develop kidney failure as a result.

SYMPTOMS

In its early stages, IgA nephropathy doesn’t normally cause any symptoms. Hence, this disease may be hard to identify, even after decades. Doctors only suspect that you have this when protein and RBCs are detected in your urine through routine tests.

Nevertheless, there are some indications for IgA include;

  • Frequent occurrence of tea or cola-colored urination
  • Blood present in the urine
  • Back pain, just below the ribs
  • High blood pressure
  • Foamy urine
  • Edema in the `hands and feet

DIAGNOSIS

In order to determine whether you have this condition or not, or if your symptoms signify a different condition, these tests may be administered:

  • Urine analysis
  • Biopsy of the kidney
  • Blood tests
  • Iotholomate clearance test

TREATMENT

Although there is no known cure for IgA nephropathy yet, a variety of treatments may be able to manage and alleviate its symptoms. The development of the condition may also be slowed down through lifestyle changes, such as keeping the cholesterol levels and blood pressure under control.

Nevertheless, the following medications may be used to manage this condition:

  • Medications for high blood pressure, such as angiotensin receptor blockers (ARBs) or angiotensin-converting enzyme (ACE)
  • Immunosuppressants
  • Diuretics
  • Omega-3 fatty acids

In addition to these, cholesterol-lowering medications may also aid in slowing down the development of kidney complications. 

Although these may not necessarily treat the condition, these medications are used to prevent the need for transplant or kidney dialysis. However, severe cases may require kidney dialysis and even a transplant.

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