Icterus (chronic familial) affects the membrane on the surface of your RBC. Instead of flattened discs with inward bends, your red blood cells now resemble spheres. Spherical cells are less elastic than regular RBCs.

The spleen initiates the immune system’s reaction to infections in a healthy body. Moreover, the spleen is in charge of removing pathogens and damaged cells from circulation. Hence, spherocytosis makes it difficult for RBC to flow through your spleen because of its shape and stiffness.

Red blood cells can be broken down more quickly by the spleen because of their irregular form. This kind of anemia is known as hemolytic anemia. Additionally, a healthy RBC can survive for up to 120 days, whereas those who have icterus (chronic familial) may only survive for ten to thirty days.


Icterus (chronic familial) can range in severity (from mild to severe.) Consequentially, the severity of the condition has an impact on symptoms. Most persons who have this ailment do so in minor cases, and those who do may not even be aware that they have.


Anemia is brought on by icterus (chronic familial icterus), which causes RBC to degrade more quickly than healthy cells. Other indications of anemia brought on by icterus include:

  • Headache
  • Fatigue
  • Dizziness
  • Shortness of breath
  • Jaundice
  • Fast heart rate
  • Heart palpitations
  • Irritability

Children’s Symptoms

Infants’ icterus may present in a number of ways (chronic familial icterus). The most common neonatal symptom, particularly during the first week of life, is jaundice rather than anemia. In addition, newborns may exhibit the following behaviors:

  • Agitated or restless
  • Sleeps extensively
  • Feeding problems


Icterus typically manifests in adolescence or early adulthood. Your doctor will inquire about the present symptoms. They will also discuss the patient’s health and family history. The likelihood is that your doctor will also ask for a blood test. Your body’s blood cell count and RBC size can be determined by a CBC test. Blood testing of other varieties might also be helpful.


Icterus (chronic familial ) can be controlled, but there is no known treatment. The kind of support you get will depend on how serious your condition is. Some potential remedies include the ones listed below:

  • Transfusion
  • Surgery
  • Vitamins
  • Light therapy
  • Vaccination

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