ICELANDIC TYPE AMYLOIDOSIS (TYPE VI)

The buildup of cerebral amyloid- (A) in the tunica media and adventitia of leptomeningeal and cortical arteries of the brain causes Icelandic type amyloidosis (type VI), which is also known as cerebral amyloid angiopathy. Lobar intracerebral hemorrhage is a common symptom of the resulting vascular fragility in normotensive elderly people. It’s a type of amyloid deposition disease that’s similar to Alzheimer’s.

SYMPTOMS

Icelandic type amyloidosis (type VI) can result in brain hemorrhage. The lobes, rather than the deep portions of the brain, are where most bleeding occurs. Since bleeding in the brain damages brain tissue, signs develop. Some people develop memory issues over time. When a CT scan is performed, there are symptoms that they may have had a brain hemorrhage that they were unaware of.

If there is a lot of blood, there are acute symptoms that look like a stroke. These signs and symptoms include:

  • Headache
  • Drowsiness
  • Seizures
  • Vomiting
  • Nervous system changes
  • Coma

If the bleeding is not serious or extensive, the following symptoms may occur:

  • Seizures
  • Headaches that come and go
  • Weakness
  • Confusions
  • Dementia

DIAGNOSIS

Without a sample of brain tissue, diagnosing Icelandic type amyloidosis (type VI) is difficult. This is frequently performed after death or during a biopsy of the brain’s blood arteries.

If the bleed is minor, a physical examination may be clear. There may be some modifications in brain function. It is critical for the doctor to inquire thoroughly about the patient’s symptoms and clinical records. The physician may assume CAA based on the signs and results of the routine physical and any imaging testing.

The following are instances of imaging tests that can be performed:

  • MRA scan
  • MRI or CT scan
  • PET scan

TREATMENT

There is no recognized treatment that is successful. The treatment’s purpose is to alleviate symptoms. Rehabilitation may be required in some circumstances due to weakness or incompetence. Physical, speech and occupational therapy are examples of this.

Medicines that help with memory, including Alzheimer’s disease, are often utilized. Moreover, anti-seizure medications can be used to treat seizures, commonly known as amyloid spells.

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