In case a severe, unexplained abdominal pain persists or worsens, or occurs together with symptoms eg, fever, nausea, vomiting, changes in bowel movements, abdominal tenderness, decreased blood pressure, fainting or blood in stool, medical advice should immediately be sought.
To prevent overdosage, ensure that any other drugs taken concurrently do not contain paracetamol.
Use with caution in glucose-6-phosphate-dehydrogenase deficiency, hepatic dysfunction (eg, due to chronic alcohol abuse, hepatitis), impaired renal function, Gilbert’s syndrome and hepatocellular insufficiency. In such cases, this product should only be used under medical supervision and, if necessary, the dose should be reduced or the intervals between the individual administrations should be prolonged.
Certain hypnotics and antiepileptics (eg, glutethimide, phenobarbital, phenytoin, carbamazepine) as well as rifampicin. The same applies to potentially hepatotoxic substances and alcohol abuse.
Long-term use of paracetamol in patients being treated with oral anticoagulants is only advisable under medical supervision.