HEREDITARY ANGIOEDEMA

Hereditary angioedema is a rare hereditary disorder that causes inflammation under the skin, as well as in the lungs and gut. Moreover, this condition can occur in various areas of your body. Even though you are born with this condition, there are treatments that help control it. 

The symptoms usually begin in childhood and worsen over the adolescent years. Many people are unaware that HAE is the cause of their swelling until they reach adulthood.

The face, limbs, airways, and intestinal system are the most common parts of the body that are susceptible to swelling. In addition, stress or a minor injury might be the cause of an attack. However, the swelling usually happens without warning.

Attacks that involve the intestinal tract may cause intense vomiting, abdominal pain, and nausea. Also, the swelling in the air passage can limit breathing and can lead to dangerous blockage of the air passage.

SYMPTOMS

The primary symptom of hereditary angioedema is swelling. Moreover, this condition could occur in any part of your body, including:

  • Belly
  • Genitals
  • Feet
  • Face
  • Hands
  • Throat or mouth

Moreover, the most common symptoms of hereditary angioedema are:

DIAGNOSIS

If you have symptoms of hereditary angioedema, the doctor will ask you the following:

  • Where do you have swelling, and how often?
  • Have you had any stomach pain or surgery?
  • What changes have you observed?
  • Have you had any in your throat, tongue, neck, or face?
  • Does anybody in your family have issues with swelling?

Answering all of these questions can help your doctor determine what is causing your condition. After that, your doctor will perform a physical exam and request a blood test to confirm if your condition is hereditary angioedema or not.

TREATMENT

The treatment for hereditary angioedema will vary, depending on the severity of your condition. Moreover, doctors can prescribe these medications to prevent and treat the attacks of hereditary angioedema:

  • Lanadelumab-flyo
  • Ecallantide
  • C1 esterase inhibitor
  • Conestat alfa
  • Icatibant
  • Berotralstat 

You might also need IV fluids or oxygen to alleviate your symptoms.

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