Hacef is a third-generation cephalosporin antibiotic that works as a bactericidal in action. The drug’s antibacterial effectiveness, like that of other cephalosporins, is due to the suppression of mucopeptide synthesis in the bacterial cell wall. Moreover, Hacef has a wider spectrum of action against gram-negative bacteria than first- and second-generation cephalosporins, although it is often less effective in vitro agains sensitive staphylococci than first-generation cephalosporins.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist. 

Hacef is used in the following conditions:

  • Infection due to sensitive gm +ve & gm -ve bacteria

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information. 

Do not use Hacef in people with the following conditions:

  • Hypersensitivity

Hacef may have the following side effects:

  • Abdominal or stomach cramps or tenderness
  • Thick, white vaginal discharge that either smells mild or not at all
  • Unusual weakness or tiredness
  • Bluish color
  • Diaper rash with white patches
  • Changes in the color of the skin
  • Pain during sexual intercourse
  • Inflammation of the foot or leg
  • Bloating
  • Inflammation at the injection site
  • Vomiting
  • Nausea
  • Sudden and unusual loss of weight
  • Severe, watery, and sometimes bloody diarrhea
  • Pain
  • Itchiness in the genital area or the vagina
  • Fever
  • Tenderness
  • White patches in the tongue, throat, or the mouth
  • Increased thirst


  • Loss of appetite
  • Stomach, leg, or back pains
  • Dizziness
  • Skin rash
  • Chills
  • Hives
  • Darker urine
  • Fast heartbeat
  • Shortness of breath or breathing difficulties
  • Feelings of tingling, prickling, crawling, itching, burning, or “pins and needles”
  • Swallowing difficulties
  • General body inflammation
  • Pale skin
  • Itching
  • Nosebleeds
  • Inflammation or puffiness of the eyelids or in the face, tongue, lips, or around the eyes
  • Cough
  • Wheezing
  • Tightness in the chest
  • Large, hive-like inflammation on the lips, throat, tongue, eyelids, face, feet, sex organs, legs, or hands
  • Sore throat
  • Bleeding gums
  • Jaundice
  • Headache

Incidence not known

  • Sudden decrease in the frequency and the amount of urine
  • Jerking or twitching of the muscles
  • Chest pain
  • Weight gain
  • Irritability
  • Paralysis
  • Confusion
  • Painful or inflamed glands
  • Change in consciousness
  • Stiff neck
  • Dark brown or reddish urine
  • Loss of consciousness
  • Blurred vision
  • Diarrhea
  • Increased blood pressure
  • White spots, ulcers, or sores on the mouth or the lips
  • Drowsiness
  • Pain or difficulties in urination
  • Vaginal bleeding or increased menstrual flow
  • Cloudy or bloody urine
  • Coughing up blood
  • Unusual bruising and bleeding
  • Hallucinations
  • Agitation
  • Prolonged bleeding from cuts
  • Clay-colored stools
  • Watery or bloody diarrhea
  • Seizures
  • Troubled breathing
  • Inflammation in the lower legs, fingers, or the face
  • Nosebleeds
  • Rhythmic movement of the muscles
  • Lower side or back pain
  • Increased thirst
  • Vomiting of blood
  • Red or black, tarry stools
  • Unpleasant breath odor

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects. 

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling, particularly of the face or tongue or throat, dizziness, or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Renal impairment
  • Monitoring renal and hematological status
  • Hypersensitivity to other cephalosporins
  • History of allergy

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.


Hacef may interact with the following medicines:

  • Beta-Lactam Antibiotics
  • Probenecid
  • Aminoglycosides
  • Diuretics
  • Chloramphenicol

Inform your physician about the drugs you take, including over-the-counter medications, prescribed drugs, supplements, and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice. 

Symptoms of overdose may include the following: 

  • Asterixis
  • Neuromuscular excitability
  • Encephalopathy
  • Coma
  • Seizure activity

Seek medical help immediately.

Available Brands:

  • Ceftazidime

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