GLYBURIDE

Glyburide belongs to a class of medications called sulfonylureas. A class of drugs refers to medications that work similarly. It lowers glucose in the blood

Uses

Glyburide treats type 2 diabetes in adults together with diet and exercise.

Warnings

Glyburide can cause low blood sugar. Symptoms of low blood sugar are:

shakiness
nervousness or anxiety
sweating, chills, and clamminess
irritability or impatience
confusion
rapid or fast heart rate
lightheadedness or dizziness
intense hunger
nausea
sleepiness
blurred or impaired vision
tingling or numbness in your lips or tongue
headaches
weakness or fatigue
anger, stubbornness, or sadness
lack of coordination
nightmares or crying out during sleep
seizures
unconsciousness

Untreated low blood sugar may result to seizure, passing out, and possibly it may develop to brain damage. Low blood sugar can even be fatal that you may need to go to the emergency room. If you pass out because of a low sugar reaction or cannot swallow, someone will have to give you an injection of glucagon to treat the reaction.

Side Effects

The most common side effects that occur with glyburide include:

diarrhea
dizziness
headache
heartburn
nausea
gas

Mild side effects usually may go away within a few days or a couple of weeks. Talk to your doctor or pharmacist if the symptoms persist or worsen.

Precautions

Precautions

Before taking Glyburide, tell your doctor if you have the following condition:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances.
if you have had a severe allergic reaction (eg, a severe rash, hives, itching, breathing difficulties, dizziness) to any other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glipizide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide
if you have a history of liver, kidney, thyroid, or heart problems
if you have stomach or bowel problems (eg, stomach or bowel blockage, stomach paralysis), drink alcohol, or have had poor nutrition
if you have a certain nerve problem (autonomic neuropathy), very poor health, a high fever, a severe infection, severe diarrhea, or high blood acid levels, or have had a severe injury
if you have a history of certain hormonal problems (eg, adrenal or pituitary problems, syndrome of inappropriate secretion of antidiuretic hormone [SIADH]), low blood sodium levels, anemia, or glucose-6-phosphate dehydrogenase (G6PD) deficiency
if you will be having surgery

Interactions

Glyburide can interact with other medications, herbs, or vitamins you might be taking. It is important to notify your doctor if you’re taking any or planning to take other drug. Talk to your doctor or pharmacist if you want to know more about these interactions.

Overdose & Brands

Go to the emergency room right away or call emergency hotline if you think you’ve taken too much glyburide.

Available brands:

Allase
Amecladin
Benglycon
Euglodin
Euglotab