Precautions
Some medical conditions may interact with glipizide/metformin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, dizziness) to any other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), probenecid, sulfamethoxazole, valdecoxib, or zonisamide
- you have heart failure, especially heart failure that is treated by medicine
- if you have a history of heart problems (eg, a heart attack, heart failure), lung or breathing problems, thyroid problems, stomach or bowel problems (eg, a blockage, paralysis), adrenal or pituitary problems, or lactic acidosis
- if you have vomiting, diarrhea, poor health or nutrition, low blood calcium or vitamin B12 levels, or anemia
- if you have an infection, fever, recent injury, or moderate to severe burns
- if you drink alcohol or have a history of alcohol abuse
- if you or a family member have a condition called glucose-6-phosphate dehydrogenase (G6PD) deficiency
- if you will be having surgery or certain lab procedures
- if you take a beta-blocker (eg, propranolol)
Interactions
This drug may interact with your other medication. It may change how your medications works either helps you or increase your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.