Giant urticaria, commonly known as hives, is an enlarged and itchy skin rash. It might occur on only one body portion or cover a wide area in your body. The rash is often itchy and may vary in size from a few mm up to the size of a palm. Although the afflicted region may have varying looks over one day, the rash typically resolves within several days.

Furthermore, giant urticaria develops whenever a trigger promotes the production of large quantities of histamine and other chemical messengers into the skin. These compounds make blood vessels in the afflicted skin region dilate and leak.


  • Acute urticaria. It is acute when the rash clears entirely within six weeks.
  • Chronic urticaria. In this situation, the rash lasts longer than six weeks and typically lasts for several years.

Urticaria vasculitis, a far uncommon form of giant urticaria, may trigger blood vessels within the skin to swell. In certain circumstances, the weals are more excruciating, persist longer, and might cause a bruise.


The primary reason for giant urticaria is an infection or allergy, which may also be triggered by vibration, stress, or unexpected changes in the external environment. Meanwhile, an aberrant immune reaction leads blood vessels to leak liquid into the dermis.

The following are the symptoms of giant urticaria:

  • Welts with distinct boundaries
  • Itching and redness
  • Rash that becomes white when squeezed


By studying the rash, your doctor can be able to identify giant urticaria. They may also interview you to determine what caused your symptoms. If your doctor believes it results from an allergic response, you could be sent to an allergy center for an allergy test.

However, if you have experienced giant urticaria on most days for over six weeks, it is uncommon to have an allergic reaction. You could also be sent for a battery of tests, such as a complete blood count, to see if there is an existing root cause of your symptoms.


Treatment for giant urticaria is seldom required since the rash usually clears up within several days. If the itching is bothering you, antihistamines might assist. A brief course of steroid pills could also be required for more extreme stages. Moreover, if your urticaria persists, you could be sent to a dermatologist. 

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