Gastrointestinal stromal tumors (GIST) are a type of cancer that starts in the digestive tract and typically occurs in the small intestine and stomach. This form of tumor is hypothesized to develop from specific cells present in the gastrointestinal system known as interstitial cells of Cajal (ICCs) or their predecessors. People who are affected may get one or even more tumors. Furthermore, GISTs may occur at any age, although they are most prevalent in adults and uncommon in youngsters.
The causes for the majority of GISTs are unknown. However, few are believed to be produced by genes that the offspring get from their parents.