GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA

GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA

Gastroesophageal junction adenocarcinoma is a rare form of cancer in the esophagus or in the tube that joins the mouth and stomach. It begins in the gastroesophageal (GE) junction, the region where the esophagus and stomach adjoins together. The cancer develops out of mucus-producing cells. 

The cancer of the GE junction is close to other esophageal cancers. 

TYPES

Gastroesophageal junction adenocarcinoma has three types:.

  • Type I is found 1 to 5 centimeters above the GE junction
  • Type II is found about 1 centimeter above the GE junction and 2 centimeters below it. 
  • Type III is found 2 to 5 centimeters below the GE junction.

SYMPTOMS

  • Loss of weight without trying 
  • A scratchy voice 
  • Acid reflux 
  • Pale face, difficulty holding the breath, and other anemia signs 
  • Trouble swallowing or chewing hard foods.

 

 

 

DIAGNOSIS

Your doctor will inquire about the signs and your medical condition then he will give a physical exam.

The main test used to detect it is endoscopy. After getting medication to keep you sleepy, the doctor sticks a flexible tube into your mouth and into your esophagus and stomach with a camera at the end.

You can  get a procedure called an endoscopic ultrasound that will  indicate how large the cancer tumor is. 

Other tests that can also detect  esophageal cancer and see if it has spread are:

  • Positron emission tomography (PET) scan. 
  • Computed tomography (CT) scan. 
  • Upper GI series or barium X-ray. 

TREATMENT

You have a few options for GE junction cancer therapy. What counseling you undergo depends on: 

  • The sort of cancer of the GE junction that you have 
  • If it has spread the cancer 
  • Your wellbeing overall 

The key cure for cancer that hasn’t spread is esophagectomy surgery. Your surgeon will extract the following: 

  • The part of your tumor-bearing esophagus 
  • Possibly part of your abdomen 
  • A small piece of your healthy esophagus 
  • Nodes of the lymph near the tumor 

The missing part of your esophagus will then be reconnected to your stomach by your surgeon.

Another form of surgery for this type of cancer is esophageal dilation. 

In order to destroy cancer cells or avoid their growth, radiation with high-energy X-rays is used.

To suppress cancer cells, chemotherapy or chemoradiation is often used. Take them orally or via injection.

Special medications that function against particular modifications in cells that turn them into cancer are used in targeted therapy. 

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