FUROSEMIDE - Uses Warning Side Effects Precautions Overdose and Brands - Watsons Health
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FUROSEMIDE

Furosemide is a drug that is known as a diuretic. It promotes the reabsorption of sodium and chloride in the medullary segment of the loop of Henle. It also promotes the excretion of potassium and ammonia. It enhances plasma-renin activity, and increases plasma-norepinephrine and plasma-arginine-vasopressin levels.

Furosemide is used in the treatment of the following:

Do not give furosemide to those with the following conditions:

Furosemide may have the following side effects:

  • Hyponatremia
  • Hypochloremic alkalosis
  • Hypokalemia
  • Headache
  • Drowsiness
  • Muscle cramps
  • Hypotension
  • Dry mouth
  • Thirst
  • Weakness
  • Lethargy
  • Restlessness
  • Oliguria
  • Gastrointestinal disturbances
  • Hypovolemia
  • Dehydration
  • Acute generalised exanthematous pustulosis
  • Drug rash with eosinophilia
  • Reversible or irreversible hearing impairment
  • Deafness
  • Tinnitus
  • Severe anaphylactic or anaphylactoid reactions
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Increased liver enzyme
  • Cholesterol
  • Triglyceride serum levels

Precautions

Take extra caution in patients with the following medical conditions:

  • Patient with prediabetes or DM
  • Hepatic cirrhosis
  • Gout
  • Impaired micturition
  • Renal and hepatic impairment
  • Elderly
  • Children
  • Pregnancy
  • Lactation

 

Interactions

Furosemide may interact with the following medicines:

  • Cephalosporins (e.g. cefalotin)
  • NSAIDs
  • Aminoglycoside
  • Ethacrynic acid
  • Other ototoxic drugs
  • Aliskiren
  • ACE inhibitors or angiotensin II receptor antagonists
  • Potassium-sparing diuretics
  • Cardiac glycosides
  • Antihistamines
  • Lithium
  • Antidiabetics
  • MAOIs
  • Carbamazepine
  • Indomethacin
  • Salicylates

Symptoms of overdose include the following:

  • Dehydration
  • Electrolyte disturbances
  • Hypotension and cardiac toxicity
  • Hypochloremic alkalosis
  • Hypokalemia

 

 Available Brands:

  • Edemann
  • Frusema
  • Furosan

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