FACTOR VIII + VON WILLEBRAND FACTOR is consist of two components:
Factor VIII is utilized to manage and avoid excessive bleeding that occurs in individuals (especially guys) with a medical condition called hemophilia A (low levels of factor VIII). It is additionally given before medical surgery to counteract excessive bleeding in patients with the said condition. Factor VIII is a protein that is found in blood and is responsible for coagulation and prevention of further bleeding after an injury or after surgery. Individuals with low factor VIII levels may bleed more than normal people after injury or after surgery and may have bleeding inside the body, particularly in the joints and muscles. This medicine contains man-made factor VIII (antihemophilic factor) to briefly supplement Factor VIII in the body, associated with a counteracting agent, such as immunoglobulin, that helps the man-made factor VIII last. Aside from controlling and preventing bleeding, this drug can also help ease pain and long-term damage caused by hemophilia.
Von Willebrand Factor is utilized to treat and control bleeding in individuals with von Willebrand disease. Von Willebrand factor is a protein found in the blood that makes the blood thicken and coagulate. People with this illness don’t have enough of this factor. This medicine contains a synthetic type of von Willebrand factor.
Factor VIII (FVIII) and von Willebrand factor (VWF) both play important jobs in hemostasis, as delineated by serious bleeding problems caused by their lack. Though they play a role in hemostasis, these two proteins form a tight, non-covalently connected complex. The physiological effects of this complex include changes in the FVIII heterodimeric structure, the stability of FVIII from proteolytic debasement, and the regulation of FVIII immunogenicity.
