ERYTHROMYCIN

COMMON BRAND NAME(S): Ilotycin

GENERIC NAME(S): ERYTHROMYCIN BASE

 

Description: Erythromycin inhibits protein synthesis that stops or slows down the growth bacteria.
Pharmacokinetics: 
Absorption: Variable and unreliable due to instability in gastric acid. Food may reduce absorption of the base or the stearate. Time to peak plasma concentration: 1-4 hr.
Distribution: Widely distributed into body tissues and fluids. Crosses the placenta and enters breast milk. Plasma protein binding: 70-75% (as the base), 95% (as the propionate ester).
Metabolism: Partly metabolised in the liver by CYP3A4 isoenzyme via N-demethylation to inactive, unidentified metabolites.
Excretion: Via faeces and urine (as unchanged drug). Plasma half-life: 1.5-2.5 hr.

Erythromycin, a macrolide antibiotic, treats certain eye infections (such as conjunctivitis), and prevents certain eye infections in newborns. It works by stopping the growth of bacteria. It will not work for other types of eye infections.

How to use erythromycin ophthalmic

To apply eye ointment, wash your hands first. To avoid contamination, be careful not to touch the tip of the tube or let it touch your eye, eyelid, or any other surface. Apply to the eyes only. Do not swallow or inject.

Do not wear contact lenses while you are using this medication. Sterilize contact lenses according to the manufacturer’s directions, and check with your doctor before you begin using them again.

To apply eye ointments, tilt your head back, look up, and gently pull down the lower eyelid to make a pouch. Place about a half-inch (1 centimeter) strip of ointment into the pouch as directed by your doctor. Gently close the eye and roll the eyeball in all directions to spread the medication. Try not to blink and do not rub the eye. Repeat these steps for your other eye if so directed. Wipe the tip of the ointment tube with a clean tissue to remove extra medication before recapping it. Wait several minutes for your vision to clear before driving or operating machinery.

The dosage is based on your medical condition and response to treatment. Do not increase your dose or use it more often than directed.

If you are using another kind of eye medication (such as drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the drops to enter the eye.

Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. Continue using it for the full time prescribed. Stopping the medication too soon may allow the bacteria to continue to grow, which may result in a return of the infection.

Tell your doctor if your condition persists or worsens.

Not available.

Tell your doctor or pharmacist promptly if eye stinging/burning/redness or temporary blurred vision persist or worsen.

Prolonged or repeated use of this medication may result in other types of eye infections, including fungal infections.

A very serious allergic reaction to this drug is rare.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

  • Allergic reaction to this medication.
  • Patient medical history.
  • Contact lens use.
  • Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely after application of drug.
  • Tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before having surgery.
  • Used only when clearly needed during pregnancy.
  • Consult your doctor before breast-feeding.

Consult your doctor regarding the precautions mentioned above.

Interactions

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

Keep a list of all the products you use. Share the list with your doctor and pharmacist to reduce your risk for serious medication problems.

Overdose

This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact a poison control center or emergency room immediately.

Notes

Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor directs you to do so. A different medication may be necessary in that case.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not expose this drug to high heat. Do not freeze. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Brands

Available Brands

  • Almycin [ Interhealth Care ]
  • Celsus Erythromycin [ Ashford ]
  • Ecolide [ Umedica ]
  • Erycar [ Ace ]
  • Erycortin [ Endure Medical ]
  • Ilosone/Ilosone DS [ Aspen ]
  • Pharex Erythromycin [ PPC ]
  • RiteMED Erythromycin [ RiteMED ]

Also marketed as

  • Aldricin [ Aldril ]
  • Brown & Burk Erythromycin Stearate [ Brown & Burk Phils ]
  • Erycin [ Biomedis ]
  • Erylide [ Brown & Burk Phils ]
  • Ery-Max [ AstraZeneca ]
  • Ery-V [ Vista Pharma ]
  • Fildrocin [ Lloyd ]
  • Medripol [ Virgo ]
  • Optryl [ Ashford ]
  • Pertustat [ Flamingo ]
  • Romaxin [ Prohealth ]
  • Ryebact [ Pasteur Pharma ]
  • Sensomed Erythromycin [ SENSOMED ]
  • Sorestin [ Pasteur Pharma ]
  • Stiemycin [ Stiefel ]
  • Upperzin [ Randril ]
  • Zaness MP [ Medhaus ]

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