HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

ELBASVIR + GRAZOPREVIR

Elbasvir and Grazoprevir both decrease the viral load of hepatitis C infection (HCV) by different activities at various stages in the viral lifecycle. Elbasvir represses HCV nonstructural protein 5A (NS5A), which is fundamental for viral RNA replication and virion assembly. Grazoprevir inhibits the action of HCV NS3/4A protease, thus forestalling the proteolytic cleavage of HCV encoded polyprotein into mature forms, and viral replication.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Elbasvir and grazoprevir are used in the following condition:

  • Chronic hepatitis C virus genotypes 1 or 4 infection

 

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Elbasvir and grazoprevir in people with the following conditions:

  • Hypersensitivity
  • Moderate to severe hepatic impairment
  • Concomitant use with organic anion transporting polypeptide 1B (OATP1B) inhibitors or strong inducers of CYP3A or P-glycoprotein (P-gp)

Elbasvir and grazoprevir may have the following side effects:

  • ALT elevations
  • Symptomatic hypoglycemia in diabetic patients
  • Nausea
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Dry mouth
  • Vomiting
  • Fatigue
  • Asthenia
  • Irritability
  • Angioedema
  • Elevated bilirubin
  • Decreased hemoglobin
  • Arthralgia
  • Myalgia
  • Headache
  • Dizziness
  • Insomnia
  • Anxiety
  • Depression
  • Pruritus
  • Alopecia
  • HBV reactivation (in HBV/HCV co-infected patients)

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

 

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Hepatitis B virus (HBV)/HCV co-infection, who completed HCV treatment, and not receiving HBV antiviral therapy or receiving immunosuppressants
  • Diabetes
  • Pregnancy
  • Lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

 

Interactions

Elbasvir and grazoprevir may interact with the following medicines:

 

  • Efavirenz
  • Phenytoin
  • Carbamazepine
  • Bosentan
  • Etravirine
  • Modafinil
  • Rifampicin
  • Nafcillin
  • Tacrolimus
  • Sunitinib
  • Atorvastatin
  • Rosuvastatin
  • Fluvastatin
  • Lovastatin
  • Simvastatin
  • Ketoconazole

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If overdose is suspected call your health care provider immediately.

Available Brands:

  • Zepatier

Related Articles

ULTRAVIST

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultravist is used in the following conditions: Radiographic Imaging: Iopromide injection is utilized to enhance the [...]

ULTRAMOX

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultramox is used in the following conditions: Respiratory Infections: Amoxicillin is often used to treat respiratory [...]

ULTRALIV

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultraliv is used in the following conditions: Carnitine Orotate: Carnitine orotate is a combination of L-carnitine [...]