Duane Syndrome is a strabismus disorder defined medically by congenital non-progressive restricted horizontal eye movement coupled with globe retraction, resulting in palpebral fissure constriction. It is caused by the absence or malfunction of the sixth cranial nerve.
The sixth cranial is a nerve that develops in the brain and regulates one of the muscles responsible for moving the eye laterally. Women seem to be more susceptible to Duane syndrome than men. In addition, the left eye is more usually afflicted than the right, and only around 10% of this disease is hereditary.