DRUG INDUCED LIVER DISEASE

DRUG INDUCED LIVER DISEASE

Drug induced liver disease is a disorder of the liver that is caused by over-the-counter-medications, doctor-prescribed medications, herbs, hormones, environmental toxins, vitamins, and recreational drugs. When the drugs harm the liver and interrupt its normal function, abnormal blood tests and liver disease symptoms may arise. 

Moreover, the drug induced liver disease abnormalities are most likely similar to liver diseases caused by immunologic illnesses and viruses. For instance, inflammation of the liver cells or drug-induced hepatitis is the same with viral hepatitis; they both cause an increase in blood levels of (ALT) or alanine aminotransferase and (AST) or aspartate aminotransferase.

SYMPTOMS

The symptoms of the drug-induced liver disease depend on the severity of the disease. Some people may experience little or no symptoms. Other people with severe disease may experience symptoms that might be specific or nonspecific. 

Furthermore, specific symptoms include:

  • Jaundice or yellowish of the skin
  • Itchiness linked with liver disease
  • Bruises and excessive bleeding

Meanwhile, nonspecific symptoms include:

  • Weakness
  • Fatigue
  • Loss of appetite
  • Abdominal pain
  • Nausea

Additionally, severe liver disease can generate symptoms associated with cirrhosis, including:

  • Fluid accumulation in the abdomen and legs
  • Coma or mental confusion
  • Kidney failure
  • Gastrointestinal bleeding
  • Vulnerability to bacterial infections

DIAGNOSIS

The diagnosis of this disease depends on a person’s symptoms. The doctor may do a physical exam and ask you regarding your problem. Also, a doctor may ask if you are experiencing symptoms like nausea, loss of appetite, itching, and fatigue.

After the doctor notices that you have drug-induced liver disease symptoms, he/she may request laboratory tests. And if a person has abnormal liver test and other symptoms, a doctor will attempt to determine what drug caused the disease by:

  • Executing abdominal ultrasound or CT scan of the liver;
  • Performing blood tests;
  • Taking a cautious history of alcohol intake; or
  • Taking a careful history of drug consumption.

TREATMENT

The most crucial treatment for liver disease is to stop taking the drug that causes it. In some individuals, symptoms and signs of liver disease will be solved, blood tests will be back to normal, and there will be no prolonged liver damage.

To prevent drug-induced liver disease, you may need to keep your liver healthy. Hence, you should consider changing your lifestyle by:

  • Eating healthy foods or a liver-friendly diet
  • Avoiding alcohol and smoking
  • Being careful when taking medicines

Related Articles

TETRALOGY OF FALLOT

Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Tetralogy of Fallot is a congenital heart defect that affects the [...]

TRICHINOSIS

Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Trichinosis, also known as trichinellosis, is a parasitic infection caused by [...]

TRIGEMINAL NEURALGIA

Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Trigeminal neuralgia is a neurological condition characterized by severe facial pain. [...]